Evidence map›Paper›PMID 33897699›Full record

ArticleFrontiers in immunology2021

High Dose IFN-

Kensei Kishimoto, Catera L Wilder, Justin Buchanan, Minh Nguyen, Chidera Okeke, Alexander Hoffmann, Quen J Cheng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kensei KishimotoInstitute for Quantitative and Computational Biosciences, University of California Los Angeles, Los Angeles, CA, United States.
Catera L WilderDepartment of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles, Los Angeles, CA, United States.
Justin BuchananDepartment of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles, Los Angeles, CA, United States.
Minh NguyenInstitute for Quantitative and Computational Biosciences, University of California Los Angeles, Los Angeles, CA, United States.
Chidera OkekeInstitute for Quantitative and Computational Biosciences, University of California Los Angeles, Los Angeles, CA, United States.
Alexander HoffmannInstitute for Quantitative and Computational Biosciences, University of California Los Angeles, Los Angeles, CA, United States.
Quen J ChengDepartment of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles, Los Angeles, CA, United States.
University of California, Los Angeles · USQB3 · US

Funding

Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5M
Coordinated dynamic regulation and function of IRF transcription factorsR01AI132835 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HOFFMANN, ALEXANDER · 2017 to 2021
$1.9M
Undergraduate Research Experience in Neuropsychiatric GenomicsR25MH109172 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ESKIN, ELEAZAR, FREIMER, NELSON B. · 2016 to 2020
$429k
NCI NIH HHS P30 CA016042NIAID NIH HHS R01 AI132835NIMH NIH HHS R25 MH109172
6 · The paper itself

Abstract

Interferon

Indexed as

AnimalsCell LineChromatin Immunoprecipitation SequencingDose-Response Relationship, ImmunologicEpithelial CellsGene Expression RegulationInterferon-betaInterferon-Stimulated Gene Factor 3MicePromoter Regions, GeneticProtein MultimerizationRNA-SeqSTAT1 Transcription FactorInterferon-betaInterferon-Stimulated Gene Factor 3Stat1 protein, mouseSTAT1 Transcription FactorGAFgene regulationinterferonISGF3JAK-STAT signaling pathwaysignal transduction

Identifiers

PMID33897699
PMCPMC8062733
OpenAlexW3152659821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.