Evidence map›Paper›PMID 33897393›Full record

ArticleFrontiers in human neuroscience2021

Early Rearing Conditions Affect Monoamine Metabolite Levels During Baseline and Periods of Social Separation Stress: A Non-human Primate Model (

Elizabeth K Wood, Natalia Gabrielle, Jacob Hunter, Andrea N Skowbo, Melanie L Schwandt, Stephen G Lindell, Christina S Barr, Stephen J Suomi, J Dee Higley

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Elizabeth K WoodDepartment of Psychology, Brigham Young University, Provo, UT, United States.
Natalia GabrielleDepartment of Psychology, Brigham Young University, Provo, UT, United States.
Jacob HunterDepartment of Neuroscience, Brigham Young University, Provo, UT, United States.
Andrea N SkowboDepartment of Psychology, Brigham Young University, Provo, UT, United States.
Melanie L SchwandtLaboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States.
Stephen G LindellLaboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States.
Christina S BarrLaboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States.
Stephen J SuomiSection of Comparative Ethology, Eunice Shriver Kennedy National Institute of Child Health and Human Development, National Institutes of Health, Poolesville, MD, United States.
J Dee HigleyDepartment of Psychology, Brigham Young University, Provo, UT, United States.
Brigham Young University · USNational Institute on Alcohol Abuse and Alcoholism · USNational Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A variety of studies show that parental absence early in life leads to deleterious effects on the developing CNS. This is thought to be largely because evolutionary-dependent stimuli are necessary for the appropriate postnatal development of the young brain, an effect sometimes termed the "experience-expectant brain," with parents providing the necessary input for normative synaptic connections to develop and appropriate neuronal survival to occur. Principal among CNS systems affected by parental input are the monoamine systems. In the present study,

Indexed as

dopamineearly rearingmonoamine metabolitesnorepinephrinerhesus macaqueserotoninserotonin transporter genotypesocial separation

Identifiers

PMID33897393
PMCPMC8062724
OpenAlexW3154164857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.