Evidence map›Paper›PMID 33897360›Full record

ArticleFrontiers in neuroscience2021

ABCA7 Regulates Brain Fatty Acid Metabolism During LPS-Induced Acute Inflammation.

Tomonori Aikawa, Yingxue Ren, Marie-Louise Holm, Yan W Asmann, Amer Alam, Michael L Fitzgerald, Guojun Bu, Takahisa Kanekiyo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. PreoperativeFrontiers in bioinformatics · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. The ABC's of Alzheimer risk gene ABCA7.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Tomonori AikawaDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL, United States.
Yingxue RenDepartment of Health Sciences Research, Mayo Clinic, Jacksonville, FL, United States.
Marie-Louise HolmDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL, United States.
Yan W AsmannDepartment of Health Sciences Research, Mayo Clinic, Jacksonville, FL, United States.
Amer AlamThe Hormel Institute, University of Minnesota, Austin, MN, United States.
Michael L FitzgeraldLipid Metabolism Unit, Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Guojun BuDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL, United States.
Takahisa KanekiyoDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL, United States.
Mayo Clinic in Florida · USHarvard University · USHormel (United States) · US

Funding

Integrative translational discovery of vascular risk factors in aging and dementiaRF1AG051504 · NIA · MAYO CLINIC JACKSONVILLE · PI BU, GUOJUN, ERTEKIN-TANER, NILUFER · 2015 to 2019
$9.8M
TECHNOLOGY NMR SPECTROSCOPYU24DK100469 · NIDDK · MAYO CLINIC ROCHESTER · PI NAIR, K SREEKUMARAN · 2013 to 2017
$9.0M
Molecular pathobiology of soluble TREM2 in Alzheimer's disease.RF1AG056130 · NIA · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI HUANG, TIMOTHY YIKAI, ZHAO, NA · 2017 to 2023
$6.8M
BRAIN LIPID METABOLISM, DENDRITES AND SYNAPSES IN AGING AND ALZHEIMER'S DISEASER01AG035355 · NIA · MAYO CLINIC JACKSONVILLE · PI BU, GUOJUN · 2010 to 2019
$3.1M
ApoE pathway in cerebrovascular Aβ clearance in Alzheimer’s diseaseR37AG027924 · NIA · MAYO CLINIC JACKSONVILLE · PI BU, GUOJUN · 2017 to 2020
$2.4M
Pathogenic mechanisms of ABCA7 in Alzheimer's diseaseR21AG054890 · NIA · MAYO CLINIC JACKSONVILLE · PI KANEKIYO, TAKAHISA · 2017 to 2018
$430k
NIA NIH HHS R01 AG035355NIA NIH HHS R21 AG054890NIA NIH HHS R37 AG027924NIA NIH HHS RF1 AG051504NIA NIH HHS RF1 AG056130NIDDK NIH HHS U24 DK100469
6 · The paper itself

Abstract

The ATP binding cassette subfamily A member 7 (

Indexed as

ABCA7Alzheimer’s diseasefatty acidsinflammationlipopolysaccharidemetabolomics

Identifiers

PMID33897360
PMCPMC8059705
OpenAlexW3149746511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.