ArticleMicrochemical journal : devoted to the application of microtechniques in all branches of science2021
Current state of diagnostic, screening and surveillance testing methods for COVID-19 from an analytical chemistry point of view.
Article in Microchemical journal : devoted to the application of microtechniques in all branches of science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Article
- Clinical performance evaluation of TAQPATH Enteric Bacterial Select Panel for the detection of common enteric bacterial pathogens in comparison to routine stool culture and other qPCR-based diagnostic tests.Microbiology spectrum · 2024Article
- Article
- Faradaic Impedimetric Immunosensor for Label-Free Point-of-Care Detection of COVID-19 Antibodies Using Gold-Interdigitated Electrode Array.Biosensors · 2023Article
- A Screening Program for SARS-CoV-2 among University of Hawai'i at Mānoa Residence Hall Students during the COVID-19 Pandemic.Hawai'i journal of health & social welfare · 2023Article
- Carbon-based biosensors: Next-generation diagnostic tool for target-specific detection of SARS-CoV-2 (COVID-19).Talanta open · 2023Article
- Performance characteristics of the boson rapid SARS-cov-2 antigen test card vs RT-PCR: Cross-reactivity and emerging variants.Heliyon · 2023Article
- Label-free impedimetric immunosensor for point-of-care detection of COVID-19 antibodies.Microsystems & nanoengineering · 2023Article
- Machine Learning Successfully Detects Patients with COVID-19 Prior to PCR Results and Predicts Their Survival Based on Standard Laboratory Parameters in an Observational Study.Infectious diseases and therapy · 2023Article
- An update on lateral flow immunoassay for the rapid detection of SARS-CoV-2 antibodies.AIMS microbiology · 2023Review
- Cross-sectional Ct distributions from qPCR tests can provide an early warning signal for the spread of COVID-19 in communities.Frontiers in public health · 2023Article
- Epidemiology, clinical presentation and treatment outcomes in patients with COVID-19 in an ambulatory setting: a cross sectional study during the massive SARS-CoV-2 wave in India.Bioinformation · 2023Article
- Recent advances of nanotechnology in COVID 19: A critical review and future perspective.OpenNano · 2023Review
- SARS-CoV-2: Challenges in Reconverting Diagnostic Laboratories to Combat the Pandemic.Microbiology spectrum · 2022Article
- The utility of SARS-CoV-2 nucleocapsid protein in laboratory diagnosis.Journal of clinical laboratory analysis · 2022Review
- Rapid Quantification of SARS-Cov-2 Spike Protein Enhanced with a Machine Learning Technique Integrated in a Smart and Portable Immunosensor.Biosensors · 2022Article
- The evolving direct and indirect platforms for the detection of SARS-CoV-2.Journal of virological methods · 2022Review
- Denaturing and dNTPs reagents improve SARS-CoV-2 detectionF1000Research · 2022Article
- COVID-19 Detection Using the NHS Lateral Flow Test Kit.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Results of an early second PCR test performed on SARS-CoV-2 positive patients may support risk assessment for severe COVID-19.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since December 2019, we have been in the battlefield with a new threat to the humanity known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this review, we describe the four main methods used for diagnosis, screening and/or surveillance of SARS-CoV-2: Real-time reverse transcription polymerase chain reaction (RT-PCR); chest computed tomography (CT); and different complementary alternatives developed in order to obtain rapid results, antigen and antibody detection. All of them compare the highlighting advantages and disadvantages from an analytical point of view. The gold standard method in terms of sensitivity and specificity is the RT-PCR. The different modifications propose to make it more rapid and applicable at point of care (POC) are also presented and discussed. CT images are limited to central hospitals. However, being combined with RT-PCR is the most robust and accurate way to confirm COVID-19 infection. Antibody tests, although unable to provide reliable results on the status of the infection, are suitable for carrying out maximum screening of the population in order to know the immune capacity. More recently, antigen tests, less sensitive than RT-PCR, have been authorized to determine in a quicker way whether the patient is infected at the time of analysis and without the need of specific instruments.
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