Evidence map›Paper›PMID 33896867›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Discrepant Diagnostic Results of Nested Polymerase Chain Reaction-based Genotyping in a Patient with Hepatitis C Virus and Human Immunodeficiency Virus Coinfection.

Masami Minemura, Kazuto Tajiri, Yuka Hayashi, Naoki Takahashi, Kasumi Watanabe, Tatsuyuki Hanaoka, Yasuhiro Araki, Kosuke Takahashi, Terumi Takahara, Shigeyuki Kojima and 1 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Masami MinemuraDepartment of Gastroenterology, Toyama University Hospital, Japan.
Kazuto TajiriDepartment of Gastroenterology, Toyama University Hospital, Japan.
Yuka HayashiDepartment of Gastroenterology, Toyama University Hospital, Japan.
Naoki TakahashiDepartment of Gastroenterology, Toyama University Hospital, Japan.
Kasumi WatanabeDepartment of Gastroenterology, Toyama University Hospital, Japan.
Tatsuyuki HanaokaDepartment of Gastroenterology, Toyama University Hospital, Japan.
Yasuhiro ArakiDepartment of Gastroenterology, Toyama University Hospital, Japan.
Kosuke TakahashiDepartment of Gastroenterology, Toyama University Hospital, Japan.
Terumi TakaharaDepartment of Gastroenterology, Toyama University Hospital, Japan.
Shigeyuki KojimaDivision of Advanced Technology and Development, BML Inc, Japan.
Ichiro YasudaDepartment of Gastroenterology, Toyama University Hospital, Japan.
Toyama University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate genotyping is important to improve the treatment of hepatitis C virus (HCV) infection. We herein report a 44-year-old Japanese man with hemophilia A and coinfection of HCV and human immunodeficiency virus (HIV) who was diagnosed with HCV genotype 4 by direct sequencing. Two genotyping tests based on the nested polymerase chain reaction method that we used misdiagnosed his genotype as 2b and 1b. Although several HCV genotyping tests are available in Japan, it is important to recognize that some cannot detect genotype 4. Care should be taken when genotyping HCV patients who have received non-heated coagulation factor preparations or were infected abroad.

Indexed as

CoinfectionHepatitis CHIV InfectionsAdultGenotypeHepacivirusHIVHumansMalePolymerase Chain Reactiondirect-acting antiviral agentgenotype 4genotypinghepatitis C virus

Identifiers

PMID33896867
PMCPMC8580760
OpenAlexW3159658779

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.