Evidence map›Paper›PMID 33896688›Full record

ReviewTrends in microbiology2021

Durability of Immunity to SARS-CoV-2 and Other Respiratory Viruses.

Matthew K Siggins, Ryan S Thwaites, Peter J M Openshaw

Erratum issuedOpen access · bronzeAbstract readReview
In one paragraph

Review in Trends in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Waning immunity drives respiratory virus evolution and reinfection.Evolution, medicine, and public health · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Biotechnologia · 2023
    Article
  20. Adaptive Immunity to Viruses: What Did We Learn from SARS-CoV-2 Infection?International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Matthew K SigginsNational Heart and Lung Institute, Imperial College London, London, UK. Electronic address: m.siggins@imperial.ac.uk.
Ryan S ThwaitesNational Heart and Lung Institute, Imperial College London, London, UK.
Peter J M OpenshawNational Heart and Lung Institute, Imperial College London, London, UK. Electronic address: p.openshaw@imperial.ac.uk.
Lung Institute · USImperial College London · GB

Funding

Medical Research Council MC_PC_19059Medical Research Council MR/V028448/1
6 · The paper itself

Abstract

Even in nonpandemic times, respiratory viruses account for a vast global burden of disease. They remain a major cause of illness and death and they pose a perpetual threat of breaking out into epidemics and pandemics. Many of these respiratory viruses infect repeatedly and appear to induce only narrow transient immunity, but the situation varies from one virus to another. In the absence of effective specific treatments, understanding the role of immunity in protection, disease, and resolution is of paramount importance. These problems have been brought into sharp focus by the coronavirus disease 2019 (COVID-19) pandemic. Here, we summarise what is now known about adaptive immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and draw comparisons with immunity to other respiratory viruses, focusing on the longevity of protective responses.

Indexed as

Adaptive ImmunityAntibodies, ViralCOVID-19HumansRespiratory Tract InfectionsSARS-CoV-2Time FactorsVirusesAntibodies, ViralCOVID-19immune responsesimmunityinfectionrespiratory virusesSARS-CoV-2

Identifiers

PMID33896688
PMCPMC8026254
OpenAlexW3145742651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.