Evidence map›Paper›PMID 33896475›Full record

ReviewSeminars in nephrology2021

Nonpharmacologic Treatments for Opioid Reduction in Patients With Advanced Chronic Kidney Disease.

Carrie E Brintz, Martin D Cheatle, Laura M Dember, Alicia A Heapy, Manisha Jhamb, Amanda J Shallcross, Jennifer L Steel, Paul L Kimmel, Daniel Cukor, HOPE Consortium

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Seminars in nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Carrie E BrintzDivision of Pain Medicine, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN. Electronic address: carrie.brintz@vumc.org.
Martin D CheatleDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Laura M DemberRenal, Electrolyte and Hypertension Division, Department of Medicine, University of Pennsylvania, Philadelphia, PA; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Alicia A HeapyPain Research Informatics Multimorbidities and Education Center of Innovation, Veterans' Affairs Connecticut Healthcare System, West Haven, CT; Department of Psychiatry, Yale School of Medicine, New Haven, CT.
Manisha JhambRenal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, PA.
Amanda J ShallcrossDepartment of Population Health, New York University School of Medicine, New York, NY.
Jennifer L SteelDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA; Department of Psychology, University of Pittsburgh, Pittsburgh, PA; Behavioral Health, The Rogosin Institute, New York, NY.
Paul L KimmelNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Daniel CukorBehavioral Health, The Rogosin Institute, New York, NY.
HOPE Consortium
University of Pennsylvania · USUniversity of Pittsburgh · USNational Institutes of Health · USNew York University · USThe Rogosin Institute · USVA Connecticut Healthcare System · USVanderbilt University Medical Center · US

Funding

UPENN Scientific and Data Research Center for the HOPE Consortium to Reduce Pain and Opioid Use in Hemodialysis U01DK123813 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI DEMBER, LAURA M, FARRAR, JOHN T · 2019 to 2024
$6.6M
Randomized ESRD Trial COmparing CBT alone VERsus with buprenorphine (RECOVER)U01DK123786 · NIDDK · UNIVERSITY OF WASHINGTON · PI CUKOR, DANIEL, MEHROTRA, RAJNISH · 2019 to 2022
$3.4M
Pain Reduction and Opioid MedIcation Safety in ESRD (PROMISE) studyU01DK123812 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JHAMB, MANISHA, LIEBSCHUTZ, JANE M · 2019 to 2020
$3.1M
Pain, Opioids, and ESRD risk reduction with Mindfulness and Buprenorphine (POEM-B): A 3-arm multi-site randomized trial in hemodialysis patientsU01DK123814 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHARYTAN, DAVID M, LEE, JOSHUA D · 2019 to 2019
$2.9M
Vanderbilt-West Virginia (VWV) Collaborative: A HOPE Consortium Clinical CenterU01DK123821 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CAVANAUGH, KERRI · 2019 to 2019
$2.9M
Video-Telecare Collaborative Pain Management to Improve Function and Reduce Opioid Risk in Patients with End Stage Renal Disease Receiving HemodialysisU01DK123817 · NIDDK · YALE UNIVERSITY · PI BECKER, WILLIAM C, CROWLEY, SUSAN T · 2019 to 2019
$2.6M
A telephone-delivered mindfulness intervention for patients with comorbid depression and chronic diseaseK23AT009208 · NCCIH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHALLCROSS, AMANDA J · 2016 to 2020
$836k
NCCIH NIH HHS K23 AT009208NIDDK NIH HHS U01 DK123786NIDDK NIH HHS U01 DK123812NIDDK NIH HHS U01 DK123813NIDDK NIH HHS U01 DK123814NIDDK NIH HHS U01 DK123817NIDDK NIH HHS U01 DK123821
6 · The paper itself

Abstract

Opioid analgesics carry risk for serious health-related harms in patients with advanced chronic kidney disease (CKD) and end-stage kidney disease. In the general population with chronic noncancer pain, there is some evidence that opioid reduction or discontinuation is associated with improved pain outcomes; however, tapering opioids abruptly or without providing supportive interventions can lead to physical and psychological harms and relapse of opioid use. There is emerging evidence that nonpharmacologic treatments such as psychosocial interventions, acupuncture, and interdisciplinary pain management programs are effective approaches to support opioid dose reduction in patients experiencing persistent pain, but research in this area still is relatively new. This review describes the current evidence for nonpharmacologic interventions to support opioid reduction in non-CKD patients with pain and discusses the application of the available evidence to patients with advanced CKD who are prescribed opioids to manage pain.

Indexed as

Chronic PainRenal Insufficiency, ChronicAnalgesics, OpioidChronic DiseaseHumansPain ManagementAnalgesics, Opioiddialysiskidney diseasenonpharmacological treatmentOpioid reductionpain

Identifiers

PMID33896475
PMCPMC9366727
OpenAlexW3159778532

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.