Evidence map›Paper›PMID 33896441›Full record

ArticleJournal of the International Neuropsychological Society : JINS2022

Assessing Bias in Cognitive Testing for Older Adults with Sensory Impairment: An Analysis of Differential Item Functioning in the Baltimore Longitudinal Study on Aging (BLSA) and the Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS).

E Nichols, J A Deal, B K Swenor, A G Abraham, N M Armstrong, M C Carlson, M Griswold, F R Lin, T H Mosley, P Y Ramulu and 4 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. ReacStick: Evaluating Executive Function Independent From Level of Education.American journal of physical medicine & rehabilitation · 2026
    Article
  5. Article
  6. Observational
  7. Sensory impairment and dementia risk among older adults in rural South Africa.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  8. Article
  9. Article
  10. Sensory and motor deficits as contributors to early cognitive impairment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  11. Cognitive change in prevalent and incident hearing loss: The Maastricht Aging Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  12. Hearing loss and cognition: A protocol for ensuring speech understanding before neurocognitive assessment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

E NicholsDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, W6508, Baltimore, MD, 21205, USA.ORCID 0000-0002-9005-3872
J A DealDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, W6508, Baltimore, MD, 21205, USA.
B K SwenorDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, W6508, Baltimore, MD, 21205, USA.
A G AbrahamDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, W6508, Baltimore, MD, 21205, USA.
N M ArmstrongDepartment of Psychiatry and Human Behavior, Brown University Warren Alpert Medical School, 700 Butler Dr, Box G-BH, Providence, RI02906, USA.ORCID 0000-0002-2479-1076
M C CarlsonDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway St, 8th Floor, Baltimore, MD21205, USA.
M GriswoldMemory Impairment and Neurodegenerative Dementia Center, University of Mississippi Medical Center, 2500 North State St, Jackson, MS39216, USA.
F R LinDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, W6508, Baltimore, MD, 21205, USA.
T H MosleyMemory Impairment and Neurodegenerative Dementia Center, University of Mississippi Medical Center, 2500 North State St, Jackson, MS39216, USA.
P Y RamuluWilmer Eye Institute, Johns Hopkins Hospital, 1800 Orleans St, Baltimore, MD21287, USA.
N S ReedDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, W6508, Baltimore, MD, 21205, USA.
S M ResnickLaboratory of Behavioral Neuroscience, National Institute on Aging, 251 Bayview Blvd, Suite 101, Baltimore, MD21224, USA.
A R SharrettDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, W6508, Baltimore, MD, 21205, USA.
A L GrossDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, W6508, Baltimore, MD, 21205, USA.
Johns Hopkins University · USUniversity of Mississippi Medical Center · USBrown University · USJohns Hopkins Hospital · USNational Institute on Aging · US

Funding

ARIC Neurocognitive Study (ARIC-NCS) Renewal 2023-2028U01HL096812 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JOSEF CORESH, THOMAS H MOSLEY · 2010 to 2026
$65.7M
Research Education ComponentP30AG066507 · NIA · JOHNS HOPKINS UNIVERSITY · PI JUAN TRONCOSO · 2020 to 2026
$29.3M
Early Markers of Alzheimer DiseaseZIAAG000185 · NIA · NATIONAL INSTITUTE ON AGING · PI WALKER, KEENAN · 2009 to 2025
$20.4M
EPIDEMIOLOGY AND BIOSTATISTICS OF AGINGT32AG000247 · NIA · JOHNS HOPKINS UNIVERSITY · PI Karen J. Bandeen-Roche · 1996 to 2026
$13.2M
ARIC Neurocognitive Study (ARIC-NCS) Renewal 2 of 5U01HL096917 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI MOSLEY, THOMAS H · 2010 to 2018
$11.9M
ARIC Neurocognitive Study (ARIC-NCS) Renewal UNC 4 of 5U01HL096899 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COUPER, DAVID J · 2010 to 2018
$7.5M
ARIC Neurocognitive Study (ARIC-NCS)U01HL096902 · NHLBI · UNIVERSITY OF MINNESOTA · PI LUTSEY, PAMELA L. · 2010 to 2018
$7.4M
Remote Data Enclave Core (RDEC)P30AG066587 · NIA · JOHNS HOPKINS UNIVERSITY · PI DANIEL E POLSKY, Jennifer L. Wolff · 2020 to 2026
$6.7M
ARIC Neurocognitive Study (ARIC-NCS) Renewal 4 of 5U01HL096814 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUGHES, TIMOTHY M., WAGENKNECHT, LYNNE E · 2010 to 2018
$6.5M
Optimizing Safety and Functionality in the Visually ImpairedR01EY022976 · NEI · JOHNS HOPKINS UNIVERSITY · PI RAMULU, PRADEEP YAMMANURU · 2013 to 2024
$5.2M
The ARIC and Neurocognitive Longitudinal StudyR01HL070825 · NHLBI · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI MOSLEY, THOMAS H · 2002 to 2004
$5.1M
Understanding sex differences and the impact of image quality on OCT-derived measures of retinal microvascular health as surrogates of brain pathology for cognitive disease.R01AG052412 · NIA · JOHNS HOPKINS UNIVERSITY · PI ABRAHAM, ALISON G, RAMULU, PRADEEP YAMMANURU · 2016 to 2019
$2.6M
NEI NIH HHS R01 EY022976NHLBI NIH HHS HHSN268201700001CNHLBI NIH HHS HHSN268201700001INHLBI NIH HHS HHSN268201700002CNHLBI NIH HHS HHSN268201700002INHLBI NIH HHS HHSN268201700003CNHLBI NIH HHS HHSN268201700003INHLBI NIH HHS HHSN268201700004CNHLBI NIH HHS HHSN268201700004INHLBI NIH HHS HHSN268201700005CNHLBI NIH HHS HHSN268201700005INHLBI NIH HHS R01 HL070825NHLBI NIH HHS U01 HL096812NHLBI NIH HHS U01 HL096814NHLBI NIH HHS U01 HL096899NHLBI NIH HHS U01 HL096902NHLBI NIH HHS U01 HL096917NIA NIH HHS K01 AG050699NIA NIH HHS K01 AG052640NIA NIH HHS K01 AG054693NIA NIH HHS P30 AG066507NIA NIH HHS P30 AG066587NIA NIH HHS R01 AG052412NIA NIH HHS R21 AG060243NIA NIH HHS T32 AG000247
6 · The paper itself

Abstract

objectivesVision and hearing impairments affect 55% of people aged 60+ years and are associated with lower cognitive test performance; however, tests rely on vision, hearing, or both. We hypothesized that scores on tests that depend on vision or hearing are different among those with vision or hearing impairments, respectively, controlling for underlying cognition.

methodsLeveraging cross-sectional data from the Baltimore Longitudinal Study of Aging (BLSA) and the Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS), we used item response theory to test for differential item functioning (DIF) by vision impairment (better eye presenting visual acuity worse than 20/40) and hearing impairment (better ear .5-4 kHz pure-tone average > 25 decibels).

resultsWe identified DIF by vision impairment for tests whose administrations do not rely on vision [e.g., Delayed Word Recall both in ARIC-NCS: .50 logit difference between impaired and unimpaired (p = .04) and in BLSA: .62 logits (p = .02)] and DIF by hearing impairment for tests whose administrations do not rely on hearing [Digit Symbol Substitution test in BLSA: 1.25 logits (p = .001) and Incidental Learning test in ARIC-NCS: .35 logits (p = .001)]. However, no individuals had differences between unadjusted and DIF-adjusted measures of greater than the standard error of measurement.

conclusionsDIF by sensory impairment in cognitive tests was independent of administration characteristics, which could indicate that elevated cognitive load among persons with sensory impairment plays a larger role in test performance than previously acknowledged. While these results were unexpected, neither of these samples are nationally representative and each has unique selection factors; thus, replication is critical.

Indexed as

AtherosclerosisCognitive DysfunctionHearing LossAgedAgingBaltimoreCross-Sectional StudiesHumansLongitudinal StudiesNeuropsychological TestsBiasCognitionEpidemiologyHearing lossLow visionNeuropsychological tests

Identifiers

PMID33896441
PMCPMC8546003
OpenAlexW3158172071

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.