Evidence map›Paper›PMID 33896360›Full record

ArticleRenal failure2021

Birthweight predicts glomerular filtration rate in adult-life: population based cross sectional study.

Issa Al Salmi, Suad Hannawi

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Renal failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Issa Al SalmiThe Medicine Department, The Royal Hospital, Muscat, Oman.ORCID https://orcid.org/0000-0002-3443-5972
Suad HannawiThe Medicine Department, MOHAP, Dubai, UAE.ORCID https://orcid.org/0000-0002-5689-6710
Royal Hospital · OM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWorldwide, there is a global progressive rise of chronic kidney disease. In parallel, children born after intra-uterine growth retardation are surviving to adult-life and beyond. This study describes the association of birthweight with and estimated glomerular filtration rate (eGFR).

methodsAustralian Diabetes, Obesity and Lifestyle (AusDiab) study participants were asked to complete a birthweight questionnaire. The associations between birthweight and eGFR were determined.

resultsA total of 4502 reported information related to their birthweight, with the other responders did not provide a value. The birthweight of the participants ranged from 0.4 to 7.0 kg with a mean-(SD) of 3.37 (0.7) kg. The mean (95%CI) birthweight was lower for females, 3.28 (0.6) kg, when compared to males, 3.5 (0.7) kg. Eight percent had a birthweight less than 2.5 kg. The eGFR was strongly and positively associated with birthweight, with people in the lowest sex-specific birthweight-quintiles having the lowest mean eGFR. This relationship persisted with adjustment for confounding factors. The OR(CI) for eGFR <10th-percentile (<61.4 ml/min for females and <73.4 for males) for people in the lowest vs. the higher birthweight-quintile was 2.19 (95%CI 1.14-4.2) for females and 2.37 (1.1-5.3) for males, after adjustment for other factors.

conclusionsBirthweight had a positive relationship with eGFR. Possible explanations include an association of birthweight with nephron-endowment. From a global health perspective but more in developing countries and in populations in epidemiologic transition, where substantially lower birthweights coexist with recently improved infant and adult survivals, the overall impact of this phenomenon on the population health profile could be more substantial.

Indexed as

AlbuminuriaAustraliaBirth WeightCross-Sectional StudiesFemaleFetal Growth RetardationGlomerular Filtration RateHumansInfant, Low Birth WeightInfant, NewbornLongitudinal StudiesMaleMiddle AgedPredictive Value of TestsPregnancyPrognosisalbumin creatine ratio (ACR)Birth weight (BW)estimated glomerular filtration rate (eGFR)intra-uterine growth retardation (IUGR)low birth weight (LBW)non-communicable diseases (NCD)

Identifiers

PMID33896360
PMCPMC8079063
OpenAlexW3159016838

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.