Evidence map›Paper›PMID 33896185›Full record

ArticleBioconjugate chemistry2021

Chemiluminescence Detection of Hydrogen Sulfide Release by β-Lactamase-Catalyzed β-Lactam Biodegradation: Unprecedented Pathway for Monitoring β-Lactam Antibiotic Bacterial Resistance.

Sachin Popat Gholap, Chunyan Yao, Ori Green, Matej Babjak, Pavol Jakubec, Tomáš Malatinský, Julian Ihssen, Lukas Wick, Urs Spitz, Doron Shabat

Open access · hybridAbstract read
In one paragraph

Article in Bioconjugate chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Sachin Popat GholapSchool of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978 Israel.
Chunyan YaoBiosynth Carbosynth, Rietlistrasse 4 Postfach 125 9422 Staad, Switzerland.
Ori GreenSchool of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978 Israel.
Matej BabjakDepartment of Organic Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Radlinského 9, 81237 Bratislava, Slovakia.
Pavol JakubecAuchem s.r.o., A. Hlinku 1452/3, 022 01 Čadca, Slovakia.
Tomáš MalatinskýAuchem s.r.o., A. Hlinku 1452/3, 022 01 Čadca, Slovakia.
Julian IhssenBiosynth Carbosynth, Rietlistrasse 4 Postfach 125 9422 Staad, Switzerland.
Lukas WickBiosynth Carbosynth, Rietlistrasse 4 Postfach 125 9422 Staad, Switzerland.
Urs SpitzBiosynth Carbosynth, Rietlistrasse 4 Postfach 125 9422 Staad, Switzerland.
Doron ShabatSchool of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978 Israel.ORCID 0000-0003-2502-639X
Tel Aviv University · ILAuchem (Slovakia) · SKSlovak University of Technology in Bratislava · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-Lactamase positive bacteria represent a growing threat to human health because of their resistance to commonly used antibiotics. Therefore, development of new diagnostic methods for identification of β-lactamase positive bacteria is of high importance for monitoring the spread of antibiotic-resistant bacteria. Here, we report the discovery of a new biodegradation metabolite (H

Indexed as

Anti-Bacterial Agentsbeta-Lactamasesbeta-LactamsHydrogen SulfideLuminescent MeasurementsBacteriabeta-Lactam ResistanceDrug Resistance, BacterialAnti-Bacterial Agentsbeta-Lactamasesbeta-LactamsHydrogen Sulfide

Identifiers

PMID33896185
PMCPMC8382227
OpenAlexW3158482997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.