Evidence map›Paper›PMID 33896086›Full record

ArticleEuropean journal of neurology2021

Impact of the COVID-19 pandemic on access to healthcare services amongst patients with multiple sclerosis in the Lazio region, Italy.

Paola Colais, Silvia Cascini, Maria Balducci, Nera Agabiti, Marina Davoli, Danilo Fusco, Enrico Calandrini, Anna Maria Bargagli

Open access · hybridAbstract read
In one paragraph

Article in European journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. COVID-19 and Radiological Progression of Multiple Sclerosis.Diagnostics (Basel, Switzerland) · 2026
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  6. Impact of COVID-19 and system recovery in delivering healthcare to people with multiple sclerosis: a population-based Study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
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  7. Review
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  10. Exploring COVID-19 experiences for persons with multiple sclerosis and carers: An Australian qualitative study.Health expectations : an international journal of public participation in health care and health policy · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paola ColaisDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.
Silvia CasciniDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.
Maria BalducciDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.
Nera AgabitiDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.
Marina DavoliDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.
Danilo FuscoDepartment of Health Information Systems, Lazio Regional Health Service, Rome, Italy.
Enrico CalandriniDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.
Anna Maria BargagliDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.ORCID 0000-0002-4222-5975

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeMultiple sclerosis (MS) is a complex chronic, autoimmune inflammatory disease involving multidisciplinary assessments and interventions. Access to outpatient specialist and home healthcare services was explored during the pandemic outbreak and the lockdown amongst MS patients in the Lazio region. Adherence to disease-modifying therapies (DMTs) is also described.

methodsA population-based study was conducted using regional healthcare administrative databases. A validated algorithm was used to identify MS cases over the period 2011-2018. The numbers of specialist and home-based services were compared between 2019 and 2020. The medication possession ratio was used to measure adherence to DMTs.

resultsA total of 9380 MS patients were identified (68% women). A decline in the number of outpatient care services between March and June 2020 compared to the previous year was observed, in particular for rehabilitation (-82%), magnetic resonance imaging (-56%) and neurological specialist services (-91%). Important year-to-year variations were observed in May and June 2020 in home-based nursing and medical care (-91%) and motor re-education services (-74%). Adherence to DMTs was higher in the first 4 months of 2019 compared to the same period of 2020 (67.1% vs. 57.0%).

conclusionsA notable disruption of rehabilitative therapy and home-based services as well as in DMT adherence was observed. Since the pandemic is still ongoing and interruption of healthcare services could have a major impact on MS patients, it is necessary to monitor access of MS patients to healthcare resources in order to ensure adequate treatments, including rehabilitative therapies.

Indexed as

COVID-19Multiple SclerosisCommunicable Disease ControlDelivery of Health CareFemaleHumansItalyMalePandemicsRetrospective StudiesSARS-CoV-2administrative databasescohortCOVID-19healthcaremultiple sclerosis

Identifiers

PMID33896086
PMCPMC8250799
OpenAlexW3159221382

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.