Evidence map›Paper›PMID 33895980›Full record

SynthesisNeuropsychology review2022

Repetition Priming in Individuals with Amnestic Mild Cognitive Impairment and Alzheimer's Dementia: a Systematic Review and Meta-Analysis.

Liselotte De Wit, Vitoria Piai, Pilar Thangwaritorn, Brynn Johnson, Deirdre O'Shea, Priscilla Amofa, Michael Marsiske, Roy P C Kessels, Nancy Schaefer, Glenn Smith

Open access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Neuropsychology review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Liselotte De WitDepartment of Clinical and Health Psychology, University of Florida, P.O. Box 100165, 32610-0165, Gainesville, FL, USA.
Vitoria PiaiDonders Institute for Brain, Cognition and Behaviour, Centre for Cognition, Radboud University, Thomas van Aquinostraat 4, 6525 GD, Nijmegen, Netherlands.
Pilar ThangwaritornDepartment of Clinical and Health Psychology, University of Florida, P.O. Box 100165, 32610-0165, Gainesville, FL, USA.
Brynn JohnsonDepartment of Clinical and Health Psychology, University of Florida, P.O. Box 100165, 32610-0165, Gainesville, FL, USA.
Deirdre O'SheaDepartment of Clinical and Health Psychology, University of Florida, P.O. Box 100165, 32610-0165, Gainesville, FL, USA.
Priscilla AmofaDepartment of Clinical and Health Psychology, University of Florida, P.O. Box 100165, 32610-0165, Gainesville, FL, USA.
Michael MarsiskeDepartment of Clinical and Health Psychology, University of Florida, P.O. Box 100165, 32610-0165, Gainesville, FL, USA.
Roy P C KesselsDonders Institute for Brain, Cognition and Behaviour, Centre for Cognition, Radboud University, Thomas van Aquinostraat 4, 6525 GD, Nijmegen, Netherlands. r.kessels@donders.ru.nl.ORCID 0000-0001-9500-9793
Nancy SchaeferUniversity of Florida Health Science Center Libraries, University of Florida, SW Archer Rd, 32610, Gainesville, FL, USA.
Glenn SmithDepartment of Clinical and Health Psychology, University of Florida, P.O. Box 100165, 32610-0165, Gainesville, FL, USA.
University of Florida Health · USRadboud University Nijmegen · NLUniversity of Florida Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The literature on repetition priming in Alzheimer's disease (AD) is inconsistent, with some findings supporting spared priming while others do not. Several factors may explain these inconsistencies, including AD severity (e.g., dementia vs. Mild Cognitive Impairment; MCI) and priming paradigm-related characteristics. This systematic review and meta-analysis provides a quantitative summary of repetition priming in AD. We examined the between-group standard mean difference comparing repetition priming in AD dementia or amnestic MCI (aMCI; presumably due to AD) to controls. Thirty-two studies were selected, including 590 individuals with AD dementia, 267 individuals with amnestic MCI, and 703 controls. Our results indicated that both individuals with aMCI and AD dementia perform worse on repetition priming tasks than cognitively older adults. Paradigm-related moderators suggested that the effect size between studies comparing the combined aMCI or AD dementia group to cognitively healthy older adults was the highest for paradigms that required participants to produce, rather than identify, primes during the test phase. Our results further suggested that priming in AD is impaired for both conceptual and perceptual priming tasks. Lastly, while our results suggested that priming in AD is impaired for priming tasks that require deep processing, we were unable to draw firm conclusions about whether priming is less impaired in aMCI or AD dementia for paradigms that require shallow processing.

Indexed as

Alzheimer DiseaseCognitive DysfunctionAgedHumansNeuropsychological TestsRepetition PrimingSeverity of Illness IndexAlzheimer’s diseaseImplicit MemoryMild Cognitive ImpairmentPrimingRepetition priming

Identifiers

PMID33895980
PMCPMC9090892
OpenAlexW3159805863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.