Evidence map›Paper›PMID 33895681›Full record

ArticleDrug and alcohol dependence2021

Validation of the Opioid Overdose Risk Behavior Scale, version 2 (ORBS-2).

Luther Elliott, Dev Crasta, Maria Khan, Alexis Roth, Traci Green, Andrew Kolodny, Alex S Bennett

Registry-linked trialAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06581276 (Increasing Access to Evidence-based Treatment for Chronic Pain and Opioid Use Disorder), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06581276 nacompletednot on this mapstarted 2023, after this paper: background citation

Increasing Access to Evidence-based Treatment for Chronic Pain and Opioid Use Disorder: Adapting Acceptance and Commitment Therapy for Opioid Treatment Programs

TypeinterventionalSponsorMontefiore Medical CenterRan2023 to 2024Enrolled7ConditionsOpioid Use, Opioid Use Disorder, Chronic PainArmsAcceptance and Commitment Therapy (ACT)
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luther ElliottNew York University School of Global Public Health, Center for Drug Use and HIV/HCV Research (CDUHR), United States. Electronic address: LCE201@NYU.edu.
Dev CrastaDepartment of Psychiatry, University of Rochester Medical Center, United States; VISN 2 Center of Excellence for Suicide Prevention, Department of Veterans Affairs, United States.
Maria KhanNew York University School of Medicine, Department of Population Health, United States.
Alexis RothDrexel Dornsife School of Public Health, United States.
Traci GreenBrandeis University, Heller School for Social Policy and Management, United States.
Andrew KolodnyBrandeis University, Heller School for Social Policy and Management, United States.
Alex S BennettNew York University School of Global Public Health, Center for Drug Use and HIV/HCV Research (CDUHR), United States. Electronic address: ASB19@NYU.edu.

Funding

Overdose Risk Management and Compensation in the Era of NaloxoneR01DA046653 · NIDA · NEW YORK UNIVERSITY · PI BENNETT, ALEXANDER S, ELLIOTT, LUTHER · 2018 to 2022
$4.4M
NIDA NIH HHS R01 DA046653
6 · The paper itself

Abstract

objectiveTo examine the factor structure of a revised and expanded opioid overdose risk behavior scale and assess its associations with known overdose indicators and other clinical constructs.

backgroundOpioid-related overdose remains high in the U.S. We lack strong instrumentation for assessing behavioral risk factors. We revised and expanded the opioid overdose risk behavior scale (ORBS-1) for use among a broader range of people who use opioids. SETTING & SAMPLING FRAME: Using respondent-driven sampling we recruited adults (18+) reporting current unprescribed opioid use and New York City residence.

methodParticipants (N = 575) completed the ORBS-1, ORBS-2, and a variety of clinical measures and then completed the ORBS-2 and overdose risk outcomes across monthly follow-up assessments over a 13-month period.

resultsPrincipal components analysis was used to identify six ORBS-2 subscales, Prescription Opioid Misuse, Risky Non-Injection Use, Injection Drug Use, Concurrent Opioid and Benzodiazepine Use, Concurrent Opioid and Alcohol Use, and Multiple-Drug Polysubstance Use. All subscales showed moderate non-parametric correlations with the ORBS-1 and with corresponding clinical constructs. Five of the subscales were significantly (p < .01) positively associated with self-reported non-fatal overdose. Of note, the Risky Non-Injection Use subscale was the most strongly associated with past-month overdose indicators.

conclusionsPsychometrics for the opioid overdose risk behavior subscales identified suggest the ongoing utility of risk behavioral instrumentation for epidemiological research and clinical practice focused on risk communication and minimization. Use of the entire ORBS-2 measure can provide insight into the proximal/behavioral factors of greatest concern to reduce overdose mortality.

Indexed as

Drug OverdoseOpiate OverdoseOpioid-Related DisordersAdultAnalgesics, OpioidHumansRisk-TakingAnalgesics, OpioidOpioidsOverdoseRisk behaviorsScale developmentScale validation

Identifiers

PMID33895681
PMCPMC8113089

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.