ArticleThe American journal of emergency medicine2021
On-admission anemia predicts mortality in COVID-19 patients: A single center, retrospective cohort study.
Article in The American journal of emergency medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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35 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Significant association between anemia and higher risk for COVID-19 mortality: A meta-analysis of adjusted effect estimates.The American journal of emergency medicine · 2022Pooled it
- Influential factors and predictive model of anemia in hospitalized elderly patients.Scientific reports · 2025Article
- Kidney involvement and anemia in COVID-19 infection.World journal of nephrology · 2025Review
- Association between hemoglobin and in-hospital mortality in critically ill patients with sepsis: evidence from two large databases.BMC infectious diseases · 2024Article
- The Onset of Antinuclear Antibodies (ANAs) as a Potential Risk Factor for Mortality and Morbidity in COVID-19 Patients: A Single-Center Retrospective Study.Biomedicines · 2024Article
- Assessing the Diagnostic Values of the Neutrophil-to-Lymphocyte Ratio (NLR) and Systematic Immunoinflammatory Index (SII) as Biomarkers in Predicting COVID-19 Severity: A Multicentre Comparative Study.Medicina (Kaunas, Lithuania) · 2024Article
- Peripheral blood indicators and COVID-19: an observational and bidirectional Mendelian randomization study.BMC medical genomics · 2024Observational
- SARS-CoV-2 Infection and Anemia-A Focus on RBC Deformability and Membrane Proteomics-Integrated Observational Prospective Study.Microorganisms · 2024Article
- Spatio-temporal epidemiology and associated indicators of COVID-19 (wave-I and II) in India.Scientific reports · 2024Article
- Could Anemia Impact the Severity of Infections? COVID-19 as an Example.F1000Research · 2024Article
- Identification and Prediction of Clinical Phenotypes in Hospitalized Patients With COVID-19: Machine Learning From Medical Records.JMIR formative research · 2023Article
- COVID-19 and pulmonary Tubercuiosis coinfection: three case reports from Iran.The Indian journal of tuberculosis · 2023Article
- Observational
- Anemia as a risk factor for disease progression in patients admitted for COVID-19: data from a large, multicenter cohort study.Scientific reports · 2023Article
- Thirty-Day Outcomes of Young and Middle-Aged Adults Admitted with Severe COVID-19 in Uganda: A Retrospective Cohort Study.Infection and drug resistance · 2023Article
- Clinical course of patients with severe SARS-CoV-2 infection co-treatment with Jin Si Herbal Tea in Eastern Taiwan: A retrospective cohort study.Journal of herbal medicine · 2022Article
- Blood Transfusion, All-Cause Mortality and Hospitalization Period in COVID-19 Patients: Machine Learning Analysis of National Health Insurance Claims Data.Diagnostics (Basel, Switzerland) · 2022Article
- On-Admission Anemia and Survival Rate in COVID-19 PatientsIranian biomedical journal · 2022Article
- The impact of chronic cardiovascular disease on COVID-19 clinical course.Journal of clinical and translational research · 2022Article
- Relationship of anemia with COVID-19 deaths: A retrospective cross-sectional study.Journal of anaesthesiology, clinical pharmacology · 2022Article
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10 authors at 2 institutions in 1 country.
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Abstract
objectivesWe investigated the impact of anemia based on admission hemoglobin (Hb) level as a prognostic risk factor for severe outcomes in hospitalized patients with coronavirus disease 2019 (COVID-19).
methodsA single-center, retrospective cohort study was conducted from a random sample of 733 adult patients (age ≥ 18 years) obtained from a total of 4356 laboratory confirmed SARS-CoV-2 cases who presented to the Emergency Department of Montefiore Medical Center between March-June 2020. The primary outcome was a composite endpoint of in-hospital severe outcomes of COVID-19. A secondary outcome was in-hospital all-cause mortality.
resultsAmong the 733 patients included in our final analysis, 438 patients (59.8%) presented with anemia. 105 patients (14.3%) had mild, and 333 patients (45.5%) had moderate-severe anemia. Overall, 437 patients (59.6%) had a composite endpoint of severe outcomes. On-admission anemia was an independent risk factor for all-cause mortality, (Odds Ratio 1.52, 95% CI [1.01-2.30], p = 0.046) but not for composite severe outcomes. However, moderate-severe anemia (Hb < 11 g/dL) on admission was independently associated with both severe outcomes (OR1.53, 95% CI [1.05-2.23], p = 0.028) and mortality (OR 1.67, 95% CI [1.09-2.56], p = 0.019) during hospitalization.
conclusionAnemia on admission was independently associated with increased odds of all-cause mortality in patients hospitalized with COVID-19. Furthermore, moderate-severe anemia (Hb <11 g/dL) was an independent risk factor for severe COVID-19 outcomes. Moving forward, COVID-19 patient management and risk stratification may benefit from addressing anemia on admission.
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