ReviewResuscitation2021
Evidence update for the treatment of anaphylaxis.
Review in Resuscitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 5 syntheses or guidelines pooled it, 105 citations in OpenAlex.
- Singapore First Aid Guidelines 2026.Singapore medical journal · 2026Guideline
- 2025 Korean Guidelines for Cardiopulmonary Resuscitation: Part 11. First aid.Clinical and experimental emergency medicine · 2026Guideline
- Hypersensitivity reactions to contrast media: Part 1. Management of immediate and non-immediate hypersensitivity reactions in adults. Updated guidelines by the ESUR Contrast Media Safety Committee.European radiology · 2025Guideline
- Clinical Practice Guideline: Immunotherapy for Inhalant Allergy.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024Guideline
- Risk factors for severe reactions in food allergy: Rapid evidence review with meta-analysis.Allergy · 2022Pooled it
- Processionary Moth Exposure in Europe: Toxic-Irritant and Immunoglobulin E-Mediated Endotypes, Diagnosis and Management.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026Review
- Neurological sequelae of massive bee envenomation: a rare case report of watershed cerebral infarction and hemorrhage.Annals of medicine and surgery (2012) · 2026Article
- Kounis Syndrome in the Modern Era: A Comprehensive Review of Allergic Acute Coronary Syndromes.Journal of clinical medicine · 2026Review
- Suspected remimazolam formulation-associated peri-induction anaphylaxis: two cases highlighting diagnostic complexity - Two case reports.Anesthesia and pain medicine · 2026Article
- Incidence and clinical management of paediatric emergency presentations of anaphylaxis in Alberta.Paediatrics & child health · 2026Article
- Article
- International Pain and Spine Intervention Society emergency protocols: Allergic and anaphylactic reactions.Interventional pain medicine · 2026Article
- From Sting to Strain: A Case Report of Wasp Sting-Induced Multiorgan Dysfunction Syndrome.Cureus · 2026Article
- Outcomes of sesame oral food challenges using different forms of sesame: Pediatric multicenter review.The journal of allergy and clinical immunology. Global · 2026Article
- First-Generation Antihistamine Use in Geriatric Emergency Department Patients: Retrospective Review.The western journal of emergency medicine · 2025Article
- Anaphylactic shock following intravenous ranitidine in rural Nepal: a case report.International journal of emergency medicine · 2025Article
- Evaluating the Use of Nasal Epinephrine in Anaphylaxis: Current Status.Turkish archives of pediatrics · 2025Review
- IgE and non-IgE-mediated pathways in anaphylaxis.Seminars in immunopathology · 2025Review
- Avoiding Glaucoma Surgery Through Allergen Identification by Skin Testing: A Case Report.Cureus · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
The Resuscitation Council UK has updated its Guideline for healthcare providers on the Emergency treatment of anaphylaxis. As part of this process, an evidence review was undertaken by the Guideline Working Group, using an internationally-accepted approach for adoption, adaptation, and de novo guideline development based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) evidence to decision (EtD) framework, referred to as GRADE-ADOLOPMENT. A number of significant changes have been made, which will be reflected in the updated Guideline. These include: emphasis on repeating intramuscular adrenaline doses after 5 min if symptoms of anaphylaxis do not resolve; corticosteroids (e.g. hydrocortisone) no longer being routinely recommended for the emergency treatment of anaphylaxis; interventions for reactions which are refractory to initial treatment with adrenaline; a recommendation against the use of antihistamines for the acute management of anaphylaxis; and guidance relating to the duration of observation following anaphylaxis, and timing of discharge.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.