Evidence map›Paper›PMID 33894659›Full record

ArticleNutrition research (New York, N.Y.)2021

Magnesium intake was inversely associated with hostility among American young adults.

Chen Lyu, Cari L Tsinovoi, Pengcheng Xun, Yiqing Song, Yongjia Pu, Andrea Rosanoff, Carlos Iribarren, Pamela J Schreiner, James M Shikany, David R Jacobs and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrition research (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Chen LyuDepartment of Epidemiology and Biostatistics, Indiana University, Bloomington, IA, USA.
Cari L TsinovoiDepartment of Epidemiology and Biostatistics, Indiana University, Bloomington, IA, USA.
Pengcheng XunDepartment of Epidemiology and Biostatistics, Indiana University, Bloomington, IA, USA.
Yiqing SongDepartment of Epidemiology, Indiana University Richard M. Fairbanks School of Public Health, Indianapolis, IA, USA.
Yongjia PuDepartment of Epidemiology and Biostatistics, Indiana University, Bloomington, IA, USA.
Andrea RosanoffCenter for Magnesium Education and Research, Pahoa, HI, USA.
Carlos IribarrenKaiser Permanente Division of Research, Oakland, CA, USA.
Pamela J SchreinerDivision of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA.
James M ShikanyDivision of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
David R JacobsDivision of Epidemiology, University of Minnesota, Minneapolis, MN, USA.
Ka KaheDepartment of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, NY 10032, USA. Electronic address: kk3399@columbia.edu.
Indiana University Bloomington · USUniversity of Minnesota · USColumbia University Irving Medical Center · USIndiana University – Purdue University Indianapolis · USKaiser Permanente · USUniversity of Alabama at Birmingham · US

Funding

Trace mineral levels, the trajectory of cognitive decline and telomere attritionRF1AG056111 · NIA · TRUSTEES OF INDIANA UNIVERSITY · PI KAHE, KA · 2017 to 2017
$3.1M
Trace element levels and risk of strokeR01ES021735 · NIEHS · TRUSTEES OF INDIANA UNIVERSITY · PI KAHE, KA, MCCLURE, LESLIE AIN · 2012 to 2016
$2.3M
Trace mineral levels, metabolomics, and diabetes riskR01DK116603 · NIDDK · TRUSTEES OF INDIANA UNIVERSITY · PI KAHE, KA · 2018 to 2019
$1.5M
Trace Elements and CVD Risks Factors Among Young AdultsR01HL081572 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAHE, KA · 2006 to 2008
$1.2M
NHLBI NIH HHS HHSN268200900041CNHLBI NIH HHS HHSN268201300025CNHLBI NIH HHS HHSN268201300026CNHLBI NIH HHS HHSN268201300027CNHLBI NIH HHS HHSN268201300029CNHLBI NIH HHS HSN268201300028CNHLBI NIH HHS R01 HL081572NIA NIH HHS RF1 AG056111NIDDK NIH HHS R01 DK116603NIEHS NIH HHS R01 ES021735
6 · The paper itself

Abstract

Hostility is a complex personality trait associated with many cardiovascular risk factor phenotypes. Although magnesium intake has been related to mood and cardio-metabolic disease, its relation with hostility remains unclear. We hypothesize that high total magnesium intake is associated with lower levels of hostility because of its putative antidepressant mechanisms. To test the hypothesis, we prospectively analyzed data in 4,716 young adults aged 18-30 years at baseline (1985-1986) from four U.S. cities over five years of follow-up using data from the Coronary Artery Risk Development in Young Adults (CARDIA) study. Magnesium intake was estimated from a dietary history questionnaire plus supplements at baseline. Levels of hostility were assessed using the Cook-Medley scale at baseline and year 5 (1990-1991). Generalized estimating equations were applied to estimate the association of magnesium intake with hostility as repeated measures at the two time-points (baseline and year 5). General linear model was used to determine the association between magnesium intake and change in hostility over 5 years. After adjustment for socio-demographic and major lifestyle factors, a significant inverse association was observed between magnesium intake and hostility level over 5 years of follow-up. Beta coefficients (95% CI) across higher quintiles of magnesium intake were 0 (reference), -1.28 (-1.92, -0.65), -1.45 (-2.09, -0.81), -1.41 (-2.08, -0.75) and -2.16 (-2.85, -1.47), respectively (P

Indexed as

DietHostilityAdolescentAdultAffectDietary SupplementsFatty Acids, Omega-3FemaleHumansMagnesiumMaleNutritional StatusProspective StudiesSurveys and QuestionnairesYoung AdultFatty Acids, Omega-3MagnesiumCARDIAGeneralized estimating equationsHostilityMagnesium intakeProspective study

Identifiers

PMID33894659
PMCPMC8098670
OpenAlexW3156395648

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.