ArticleInternational journal of pediatric otorhinolaryngology2021
Tracheal pressure generated by high-flow nasal cannula in 3D-Printed pediatric airway models.
Article in International journal of pediatric otorhinolaryngology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- Heated High-Flow Nasal Cannula Therapy for Pediatric Obstructive Sleep Apnea: Physiology, Clinical Evidence, and Future Directions.Children (Basel, Switzerland) · 2026Review
- High-flow nasal cannulaERJ open research · 2026Article
- Design and Bench Testing of a Novel, Pediatric, Non-Invasive, Bubble Bilevel Positive Pressure Ventilation Device.Bioengineering (Basel, Switzerland) · 2025Article
- Obstructive Sleep Apnea in Neonates.Children (Basel, Switzerland) · 2022Review
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveHeated and humidified high flow nasal cannula (HFNC) is an increasingly used form of noninvasive respiratory support with the potential to generate significant tracheal pressure. The aim of this study was to quantify the pressure generated by HFNC within the trachea in anatomically correct, pediatric airway models.
methods3D-printed upper airway models of a preterm neonate, term neonate, toddler, and small child were connected to a spontaneous breathing computerized lung model at age-appropriate ventilation settings. Two commercially available HFNC systems were applied to each airway model at increasing flows and the positive end-expiratory pressure (PEEP) was recorded at the level of the trachea.
resultsIncreasing HFNC flow produced a quadratically curved increase in tracheal pressure in closed-mouth models. The maximum flow tested in each model generated a tracheal pressure of 7 cm H
conclusionsHFNC was found to demonstrate a predictable flow-pressure relationship that achieved sufficient distending pressure to consider treatment of pediatric obstructive sleep apnea and tracheomalacia in the closed-mouth models tested.
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Registered trials
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