ArticlePediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology2021
Gestational diabetes and childhood asthma in a racially diverse US pregnancy cohort.
Article in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Maternal gestational diabetes mellitus and the childhood asthma in offspring: a meta-analysis.Italian journal of pediatrics · 2023Pooled it
- Heavy moms, wheezy kids: how maternal obesity harms breathing in offspring.American journal of respiratory cell and molecular biology · 2026Review
- Gestational diabetes and childhood lung function at age 8 to 9 years in a diverse US cohort.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2026Article
- Maternal dietary flavonoid intake and child wheeze and asthma in the Conditions Affecting Neurocognitive Development and Learning in Early Childhood (CANDLE) cohort.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Article
- Maternal Glycemia During Pregnancy and Child Lung Function: A Prospective Cohort Study.Diabetes care · 2024Article
- Maternal stressful life events during pregnancy and childhood asthma and wheeze.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024Article
- Multivitamin consumption and childhood asthma: a cross-sectional study of the NHANES database.BMC pediatrics · 2024Article
- Association between maternal gestational diabetes and allergic diseases in offspring: a birth cohort study.World journal of pediatrics : WJP · 2023Article
- Perinatal and early life factors and asthma control among preschoolers: a population-based retrospective cohort study.BMJ open respiratory research · 2023Article
- Maternal glycemia in pregnancy is longitudinally associated with blood DNAm variation at the FSD1L gene from birth to 5 years of age.Clinical epigenetics · 2023Article
- Relation of Maternal Pre-Pregnancy Factors and Childhood Asthma: A Cross-Sectional Survey in Pre-School Children Aged 2-5 Years Old.Medicina (Kaunas, Lithuania) · 2023Article
- Asthma in pregnancy.Allergy and asthma proceedings · 2023Review
- Cohort Study of Maternal Gestational Weight Gain, Gestational Diabetes, and Childhood Asthma.Nutrients · 2022Article
- The association between prenatal FFree radical biology & medicine · 2022Article
- Effect of Evidence-Based Diet Nursing on Intestinal Flora and Maternal and Infant Prognosis in Patients with Gestational Diabetes.Evidence-based complementary and alternative medicine : eCAM · 2022Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundChildhood asthma is a common chronic disease that likely has prenatal origins. Gestational diabetes alters maternal physiology and may influence fetal risk for childhood-onset disease. However, the association between gestational diabetes and child asthma is not well characterized.
objectiveTo investigate the association between gestational diabetes and wheeze/asthma at approximately 4 years of age in a racially diverse US cohort.
methodsWe studied mother-child dyads enrolled prenatally in the Conditions Affecting Neurocognitive Development and Learning in Early Childhood study. Gestational diabetes was determined by medical chart review. At approximately 4 years of age, we assessed child respiratory outcomes including parent report of physician-diagnosed asthma (ever), current wheeze (symptoms within the past 12 months), and current asthma (physician diagnosis and/or medication or symptoms within the past 12 months). We used the modified Poisson regression to assess associations between gestational diabetes and child respiratory outcomes, adjusting for maternal age, race, prenatal smoking, pre-pregnancy body mass index, parity, asthma history, socioeconomic status, and infant sex.
resultsAmong 1107 women, 66% were African American/Black. Six percent (n = 62) had gestational diabetes documented during pregnancy. Gestational diabetes was associated with increased risk of physician-diagnosed asthma (adjusted risk ratio (RR) [95% Confidence Interval]: 2.13 [1.35, 3.38]; prevalence: 14%), current wheeze (RR: 1.85 [1.23, 2.78]; prevalence: 19%), and current asthma (RR: 2.01 [1.30, 3.10]; prevalence: 16%).
conclusionsGestational diabetes was associated with increased risk of asthma and wheeze outcomes. Additional studies are needed to elucidate modifiable pathways underlying this association.
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