ArticlePediatric radiology2021
Technical feasibility and correlations between shear-wave elastography and histology in kidney fibrosis in children.
Article in Pediatric radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Investigating the role of ultrasound-based shear wave elastography in kidney transplanted patients: correlation between non-invasive fibrosis detection, kidney dysfunction and biopsy results-a systematic review and meta-analysis.Journal of nephrology · 2024Pooled it
- Ultrasound elastography in pediatric care: bridging innovation and noninvasive diagnostics.Italian journal of pediatrics · 2026Review
- Shear wave elastography for assessing kidneys in pediatric patients with primary nephrotic syndrome.Insights into imaging · 2025Article
- Can Broadening the Kidney Biopsy Criteria Reduce Misleading Diagnoses in Young Patients with End-Stage Renal Diseases? A Survey on the Sicilian Registry of Nephrology, Dialysis, and Transplantation.Medicina (Kaunas, Lithuania) · 2024Article
- Fibrosis in Chronic Kidney Disease: Pathophysiology and Therapeutic Targets.Journal of clinical medicine · 2024Review
- Obesity and Body Composition in Relation to Liver and Kidney Ultrasound Elastography in Paediatric Patients with Either Hypertension or Chronic Kidney Disease.Children (Basel, Switzerland) · 2023Article
- Liver and kidney ultrasound elastography in children and young adults with hypertension or chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2023Article
- Imaging fibrosis in pediatric kidney transplantation: A pilot study.Pediatric transplantation · 2023Article
- Utility of shear wave-based ultrasound elastography in chronic kidney disease and related pathological quantitative analysis.European radiology · 2023Article
- Ultrasound Elastography in Children.Children (Basel, Switzerland) · 2023Review
- Kidney tissue elastography and interstitial fibrosis observed in kidney biopsy.Renal failure · 2022Article
- Preliminary study of sound touch elastography in diffuse thyroid disease in children.Frontiers in pediatrics · 2022Article
- A Case of Shear Wave Velocity Reflecting the Disease Activity in Glomerulonephritis.Journal of medical ultrasoundArticle
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundUltrasound elastography has been suggested for assessing organ fibrosis.
objectiveTo study the feasibility of shear-wave elastography in children with kidney disease and the correlation between elasticity and kidney fibrosis in order to reduce the indications for kidney biopsy and its complications. MATERIALS AND
methodsFour operators measured kidney elasticity in children with kidney diseases or transplants, all of whom also had a renal biopsy. We assessed the feasibility and the intraobserver variability of the elasticity measurements for each probe used and each kidney explored. Then we tested the correlation between elasticity measurements and the presence of fibrosis.
resultsOverall, we analyzed 95 children and adolescents, 31 of whom had renal transplant. Measurements with the convex probe were possible in 100% of cases. Linear probe analysis was only possible for 20% of native kidneys and 50% of transplants. Intraobserver variabilities ranged from moderate to high, depending on the probe and kidney studied. Elasticity was higher with the linear probe than with the convex probe (P<0.001 for left kidney and P=0.03 for right kidney). Measurements did not differ from one kidney to another in the same child. Elasticity and fibrosis were both higher in transplant patients (P=0.02 with convex probe; P=0.01 with linear probe; P=0.04 overall). There was no correlation between elasticity and fibrosis.
conclusionOf the devices used in this work, kidney elastography was more accurately analyzed with a convex probe. Our study did not identify any correlation between elasticity and kidney fibrosis.
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