Evidence map›Paper›PMID 33893847›Full record

ArticlePediatric radiology2021

The impact of susceptibility correction on diffusion metrics in adolescents.

Katri Lahti, Riitta Parkkola, Päivi Jääsaari, Leena Haataja, Virva Saunavaara, PIPARI Study Group

Open access · hybridAbstract read
In one paragraph

Article in Pediatric radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Katri LahtiDepartment of Pediatric Neurology, University of Turku and Turku University Hospital, P.O. Box 52, 20521, Turku, Finland. kaalah@utu.fi.ORCID http://orcid.org/0000-0002-4024-9949
Riitta ParkkolaDepartment of Radiology, University of Turku and Turku University Hospital, Turku, Finland.ORCID http://orcid.org/0000-0001-8046-315X
Päivi JääsaariDepartment of Oral and Maxillofacial Diseases, Turku University Hospital, Turku, Finland.ORCID http://orcid.org/0000-0001-7960-3944
Leena HaatajaChildren's Hospital, and Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID http://orcid.org/0000-0002-8057-6194
Virva SaunavaaraDepartment of Medical Physics, Turku University Hospital, Turku, Finland.ORCID http://orcid.org/0000-0001-7858-5924
PIPARI Study Group
Turku University Hospital · FIUniversity of Turku · FIUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiffusion tensor imaging is a widely used imaging method of brain white matter, but it is prone to imaging artifacts. The data corrections can affect the measured values.

objectiveTo explore the impact of susceptibility correction on diffusion metrics. MATERIALS AND

methodsA cohort of 27 healthy adolescents (18 boys, 9 girls, mean age 12.7 years) underwent 3-T MRI, and we collected two diffusion data sets (anterior-posterior). The data were processed both with and without susceptibility artifact correction. We derived fractional anisotropy, mean diffusivity and histogram data of fiber length distribution from both the corrected and uncorrected data, which were collected from the corpus callosum, corticospinal tract and cingulum bilaterally.

resultsFractional anisotropy and mean diffusivity values significantly differed when comparing the pathways in all measured tracts. The fractional anisotropy values were lower and the mean diffusivity values higher in the susceptibility-corrected data than in the uncorrected data. We found a significant difference in total tract length in the corpus callosum and the corticospinal tract.

conclusionThis study indicates that susceptibility correction has a significant effect on measured fractional anisotropy, and on mean diffusivity values and tract lengths. To receive reliable and comparable results, the correction should be used systematically.

Indexed as

Diffusion Tensor ImagingWhite MatterAdolescentAnisotropyChildCorpus CallosumFemaleHumansMaleAdolescentsBrainDiffusion tensor imagingMagnetic resonance imagingSusceptibility correctionTractography

Identifiers

PMID33893847
PMCPMC8266789
OpenAlexW3153984409

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.