ArticleThe journal of international advanced otology2021
Evaluation of Neutrophil/Lymphocyte and Platelet/Lymphocyte Ratios in Sudden Sensorineural Hearing Loss and Relationship with Hyperbaric Oxygen Therapy.
Article in The journal of international advanced otology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.
- Association Between Hematological Indices of Inflammation and Pathogenesis and Prognosis of Sudden Sensorineural Hearing Loss: A Systematic Review and Meta-Analysis.The journal of international advanced otology · 2025Pooled it
- The value of inflammatory biomarkers in the occurrence and prognosis of sudden sensorineural hearing loss: a meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Pooled it
- Hyperbaric oxygen therapy for sudden sensorineural hearing loss (Review).Molecular medicine reports · 2025Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aimed to evaluate the prognostic value of neutrophil/lymphocyte (N/L) and platelet/lymphocyte (P/L) ratios in sudden sensorineural hearing loss (SSNHL) and investigate the effect of combined corticosteroid medical treatment and/or hyperbaric oxygen (HBO) therapy on these values. MATERIALS AND
methodsIn this study, patients with SSHL at our tertiary center were examined retrospectively. A total of 60 patients with SSNHL and 30 healthy individuals as the control group were included. The patient and control groups were compared in terms of N/L and P/L rates. Furthermore, 60 patients were divided into 2 equal groups (n=30) on the basis of whether they received HBO in addition to combined corticosteroid treatment.
resultsThe N/L and P/L rates were significantly higher in the patient groups than in the control group at the time of diagnosis and significantly decreased after treatment in the patient groups (p<0.05). It was observed that HBO therapy lowered the N/L and P/L rates more than the HBO-free group, but the statistically significant decrease was only in N/L ratio (p<0.05).
conclusionThe N/L and P/L rates were higher in the patient groups than in the control group, and there was also a significant decrease in the 2 values after treatment. This was an important finding showing that SSNHL has a possible underlying inflammatory and vascular (ischemic) condition. We also found that the higher the P/L ratio, the lower the recovery rate from hearing loss. This finding suggests that the P/L ratio can be an important prognostic indicator in patients with SSNHL.
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