Evidence map›Paper›PMID 33893771›Full record

ArticleThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2021

Retrospective Evaluation of Hepatitis C Awareness in Turkey Through Two Decades.

Hatice Yasemin Balaban, Osman Dağ, Alparslan Alp, Nomingerel Tseveldorj, Cavanşir Vahabov, Mehmet Akif Göktaş, Tuğrul Pürnak, Gülşen Hasçelik, Hülya Demir, Bülent Sivri and 1 more

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Article in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Changes in Hepatitis C Awareness in Different Disciplines During COVID-19.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hatice Yasemin BalabanInternal Medicine Department, Gastroenterology, Hacettepe University, Medical Faculty.
Osman DağBiostatistics Department, Hacettepe University, Medical Faculty.
Alparslan AlpMicrobiology and Clinical Microbiology Department, Hacettepe University, Medical Faculty.
Nomingerel TseveldorjInternal Medicine Department, Gastroenterology, Hacettepe University, Medical Faculty.
Cavanşir VahabovInternal Medicine Department, Gastroenterology, Hacettepe University, Medical Faculty.
Mehmet Akif GöktaşPediatric Health and Diseases Department, Gastroenterology, Hepatology, and Nutrition Unit, Hacettepe University, Medical Faculty.
Tuğrul PürnakInternal Medicine Department, Gastroenterology, Hacettepe University, Medical Faculty.
Gülşen HasçelikMicrobiology and Clinical Microbiology Department, Hacettepe University, Medical Faculty.
Hülya DemirPediatric Health and Diseases Department, Gastroenterology, Hepatology, and Nutrition Unit, Hacettepe University, Medical Faculty.
Bülent SivriInternal Medicine Department, Gastroenterology, Hacettepe University, Medical Faculty.
Halis ŞimşekInternal Medicine Department, Gastroenterology, Hacettepe University, Medical Faculty.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsChronic hepatitis C (CHC) is the only viral infection that can be treated with oral antiviral agents. However, CHC awareness is a major barrier to the World Health Organization's target of eliminating hepatitis C virus (HCV) by 2030. Here, CHC awareness trends were analyzed in Hacettepe University Hospital, Turkey, between January 2000 and December 2017. MATERIALS AND

methodsCentral laboratory data were retrospectively analyzed for HCV test results (anti-HCV, HCV RNA, HCV genotype). After combining 548,141 anti-HCV test results, 395,103 cases were analyzed. The following two parameters were defined for CHC awareness: (1) the presence of HCV RNA results for anti-HCV positives and (2) the presence of a genotype result for HCV RNA positives.

resultsAnti-HCV positives were older than negatives (mean age-years ± SD, 59.4 ± 19.0 vs. 44.0 ± 18.9), and the positivity rate was higher in women than in men (1.4% vs. 1.0%). Anti-HCV positivity decreased from 3.1% to 0.6% from 2000 to 2015 and subsequently stabilized. The overall percentage of RNA testing among anti-HCV positives was 53.1% (range, 20%-70%), which stabilized at approximately 50% after 2010. The genotyping rate for RNA positives varied between 40% and 70%. The main genotype identified was genotype 1 (85.7%).

conclusionIn an ideal CHC awareness state, all anti-HCV positives should undergo RNA testing, and genotyping should be performed when RNA tests are positive. However, even in our referral center, the combined rate of RNA and genotype testing was only approximately 50% during the last 10 years.

Indexed as

AwarenessHepatitis C, ChronicAdultAgedAged, 80 and overAttitude to HealthFemaleGenotypeHepacivirusHepatitis CHumansMaleMiddle AgedNational Health ProgramsRetrospective StudiesRNA, ViralRNA, Viral

Identifiers

PMID33893771
PMCPMC8975459

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.