ArticleMikrochimica acta2021
A sensitive and label-free electrochemical microRNA biosensor based on Polyamidoamine Dendrimer functionalized Polypyrrole nanowires hybrid.
Article in Mikrochimica acta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Ultrasensitive Impedimetric Biosensor for Ovarian Cancer Screening.Indian journal of microbiology · 2025Article
- Development of bismuth sulfide nanorods and polyamidoamine dendrimer on reduced graphene oxide as electrode nanomaterials for electrochemical determination of salbutamol.Scientific reports · 2023Article
- Application of Polypyrrole-Based Electrochemical Biosensor for the Early Diagnosis of Colorectal Cancer.Nanomaterials (Basel, Switzerland) · 2023Review
- Assessing Meat Freshness via Nanotechnology Biosensors: Is the World Prepared for Lightning-Fast Pace Methods?Biosensors · 2023Review
- Review
- Electrochemical DNA Sensor Based on Acridine Yellow Adsorbed on Glassy Carbon Electrode.Sensors (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The potential of functionalized polypyrrole nanowires (PPyNWs) are demonstrated as a platform for lable-free miRNA detection using electrochemical impedance spectroscopy (EIS). MicroRNAs (miRNAs) detection methods and sensors are mainly challenged by very low concentrations in physiological samples and high similarity among family members. Herein, a sensitive and selective miRNA biosensor was constructed based on electrochemically synthesized PPyNWs, which were functionalized with polyamidoamine dendrimer (PAMAM) by an electro-oxidation method. The prepared PPyNWs/PAMAM hybrid combines the excellent electrical conductivity of conducting polymer PPyNWs with high surface to volume ratio of PAMAM. DNA probes were immobilized onto the PPyNWs/PAMAM hybrid for the construction of the miRNA biosensor. Using the sensitive EIS technique to monitor DNA/miRNA hybridization, the developed biosensor demonstrated excellent sensing performances, such as wide linear range (10
Indexed as
Identifiers
33893598What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.