Evidence map›Paper›PMID 33892682›Full record

Trial reportBMC public health2021

The efficacy of a targeted PREVENTION programme for addictive behaviour (PREVENTURE) among vulnerable ADOlescents in France - study procotol.

Morgane Guillou-Landreat, Elkhan Tahmazov, Schreck Benoit, Marie Grall-Bronnec, Patricia Conrod, Audrey Livet, Emmanuel Nowak, Jean -Yves Le Reste

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04599270 (Efficiency of Prevention Program Dedicated to Addictive Behaviors), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04599270 narecruitingnot on this map

Efficiency of Prevention Program Dedicated to Addictive Behaviors (PREVENTURE) of Vulnerable Teenagers

TypeinterventionalSponsorUniversity Hospital, BrestRan2021 to 2027Enrolled700ConditionsAddiction, Alcohol, Addiction, SubstanceArmsPREVENTURE Program, Routine care
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Morgane Guillou-LandreatEA 7479 SPURBO, University of Brest, Addictive disorder centre, CHU BREST HUGOPSY network, Rennes, France. morgane.guillou@chu-brest.fr.
Elkhan TahmazovAddictive disorders Unit, CHU Brest, University of Brest, Brest, France.
Schreck BenoitAddiction and Psychiatry Department, CHU Nantes, Nantes, France.
Marie Grall-BronnecAddiction and Psychiatry Department, CHU Nantes, Nantes, France.
Patricia ConrodCHU Sainte-Justine Research Center, 3175 Côte Ste-Catherine, Montréal, H3T 1C5, Canada.
Audrey LivetCHU Sainte-Justine Research Center, 3175 Côte Ste-Catherine, Montréal, H3T 1C5, Canada.
Emmanuel NowakCentre d'Investigation Clinique-INSERM CIC 1412, CHRU, Brest, France.
Jean -Yves Le ResteEA 7479 SPURBO, University of Brest, Brest, France.
Université de Bretagne Occidentale · FRCentre Hospitalier Universitaire Sainte-Justine · CAClinical Investigation Center Plurithematic Tours · FRInserm · FRUniversité de Montréal · CAUniversité de Tours · FR

Funding

Direction Générale de l'offre de Soins PHRC-2019
6 · The paper itself

Abstract

backgroundAlcohol use is a major public health challenge in France, where at the age of 17 half the young people report an episode of severe alcohol intoxication in the month preceding the survey. Numerous prevention programmes have a general objective, but in adolescence individual vulnerabilities towards addictions differ significantly with personality traits. Prevention targeting personality traits enables work on risk factors for addictive behaviours, and has shown genuine efficacy. Among existing programmes, PREVENTURE has shown an effect on the reduction in alcohol consumption by targeting four personality traits: impulsivity, sensation-seeking, negative thoughts and anxiety. This programme has been tested on samples recruited in adolescent populations in school environments, identifying adolescents at risk, but it has not been tested on a more targeted recruitment of adolescents seen in consultation.

methodsThe main hypothesis of this study is that the targeted prevention programme PREVENTURE will have an impact on the prevalence of binge-drinking episodes. The secondary hypotheses explore other factors such as associated substance use, anxiety and depression, as well as the acceptability of the programme. This article presents the study protocol of "PREVADO" study. We intend to assess the impact of the targeted intervention programme PREVENTURE on the prevalence of binge-drinking episodes among adolescents aged 14 to 17 years consulting in one of the participating centres or referred by a school doctor. The study will be prospective, randomised, controlled and open-label, and will comprise an intervention group and a control group. The adolescents will then be followed and assessed 1, 3, 6 and 12 months after the intervention. The study needs to include 700 subjects in order to reach 340 adolescents randomised, 170 in each group. It will concern 33 centres. DISCUSSION: This project could favour the targeting of addictive behaviours among vulnerable adolescents, and its application on a larger scale could be envisaged.

trial registrationThe Trial registration number is NCT04599270 , and it was registered on the ClinicalTrials.gov public website.

Indexed as

Alcoholic IntoxicationBehavior, AddictiveAdolescentAlcohol DrinkingFranceHumansProspective StudiesAlcoholAlcohol use disorderTargeted alcohol use prevention

Identifiers

PMID33892682
PMCPMC8063443
OpenAlexW3154090370

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.