SynthesisBMC psychiatry2021
Scope, quality and inclusivity of international clinical guidelines on mental health and substance abuse in relation to dual diagnosis, social and community outcomes: a systematic review.
Synthesis in BMC psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 4 syntheses or guidelines pooled it, 93 citations in OpenAlex.
- Effectiveness of psychosocial interventions for adults with substance use disorder that have a co-occurring mental health disorder: an umbrella review and illustrative cost-effectiveness analysis.Health technology assessment (Winchester, England) · 2026Pooled it
- Prepulse inhibition deficit as a transdiagnostic process in neuropsychiatric disorders: a systematic review.BMC psychology · 2023Pooled it
- A systematic review of the perceptions and attitudes of mental health nurses towards alcohol and other drug use in mental health clients.International journal of mental health nursing · 2022Pooled it
- Associations of common mental disorder with alcohol use in the adult general population: a systematic review and meta-analysis.Addiction (Abingdon, England) · 2022Pooled it
- From Stigma to Recognition in Dual Diagnosis Care: A Multilevel Conceptual Framework.Community mental health journal · 2026Article
- Guidelines for the nursing care of patients diagnosed with dual diagnosis in psychiatric hospitals of Ghana: a qualitative study.BMC nursing · 2026Article
- WADD-SEPD Consensus on Psychological Treatment of Dual Disorders I: General Recommendations, Most Used Therapies, and Severe Mental Disorders.Journal of clinical medicine · 2026Review
- Perceptions of nurses on the current nursing care of patients with dual diagnosis in Ghana: a qualitative study.BMC nursing · 2026Article
- Organising housing and service provision for persons with co-occurring substance use and mental health problems: a scoping review in the ROP Municipal.BMC psychiatry · 2025Article
- Implementing digital interventions for co-occurring mental health and alcohol and other drug use problems in health and community settings: a study protocol for the eCliPSE cluster randomised controlled trial.BMC public health · 2025Article
- Psychoactive Substance Use and Its Association with Mental Health Symptomatology Among Latvian Medical Students: A Cross-Sectional Study.International journal of environmental research and public health · 2025Article
- The current nursing care of patients diagnosed with dual diagnosis: a comprehensive literature review.BMC nursing · 2025Article
- Barriers Experienced by Psychiatric Nurses to Facilitate Therapeutic Relationships With Mental Healthcare Users With Dual Diagnosis in a Psychiatric Hospital in South Africa.Journal of psychiatric and mental health nursing · 2025Article
- Cariprazine as a maintenance treatment in dual schizophrenia: a 6-month observational study in patients with schizophrenia and cannabis use disorder.International clinical psychopharmacology · 2025Observational
- Nationwide study of emergency care quality for patients with substance use disorders and dual diagnoses across three distinct patient populations.BMC psychiatry · 2025Article
- Global Mapping and Visualization of Substance Use Disorders and Treatment: Implications for Priority Setting.Advanced biomedical research · 2025Article
- Article
- Expectations and needs of people with illicit substance use disorders in general practice: a qualitative study in Belgium.BMC primary care · 2024Article
- Interventions targeting patients with co-occuring severe mental illness and substance use (dual diagnosis) in general practice settings - a scoping review of the literature.BMC primary care · 2024Article
- Dual diagnosis and their care pathways for help-seeking: A multicenter study from India.Indian journal of psychiatry · 2024Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIt is estimated that up to 75% of patients with severe mental illness (SMI) also have substance use disorder (SUD). The aim of this systematic review was to explore the scope, quality and inclusivity of international clinical guidelines on mental health and/or substance abuse in relation to diagnosis and treatment of co-existing disorders and considerations for wider social and contextual factors in treatment recommendations.
methodA protocol (PROSPERO CRD42020187094) driven systematic review was conducted. A systematic search was undertaken using six databases including MEDLINE, Cochrane Library, EMBASE, PsychInfo from 2010 till June 2020; and webpages of guideline bodies and professional societies. Guideline quality was assessed based on 'Appraisal of Guidelines for Research & Evaluation II' (AGREE II) tool. Data was extracted using a pre-piloted structured data extraction form and synthesized narratively. Reporting was based on PRISMA guideline.
resultA total of 12,644 records were identified. Of these, 21 guidelines were included in this review. Three of the included guidelines were related to coexisting disorders, 11 related to SMI, and 7 guidelines were related to SUD. Seven (out of 18) single disorder guidelines did not adequately recommend the importance of diagnosis or treatment of concurrent disorders despite their high co-prevalence. The majority of the guidelines (n = 15) lacked recommendations for medicines optimisation in accordance with concurrent disorders (SMI or SUD) such as in the context of drug interactions. Social cause and consequence of dual diagnosis such as homelessness and safeguarding and associated referral pathways were sparsely mentioned.
conclusionDespite very high co-prevalence, clinical guidelines for SUD or SMI tend to have limited considerations for coexisting disorders in diagnosis, treatment and management. There is a need to improve the scope, quality and inclusivity of guidelines to offer person-centred and integrated care.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.