Evidence map›Paper›PMID 33892254›Full record

ArticlePreventive veterinary medicine2021

Evidence of influenza infection in dogs and cats in central Chile.

Pedro Jimenez-Bluhm, Alejandra Sepulveda, Cecilia Baumberger, Francisca Di Pillo, Soledad Ruiz, Carla Salazar, Victor Marambio, Fernanda Berrios, Pablo Galdames, Alicia Amaro and 6 more

Open access · greenAbstract read
In one paragraph

Article in Preventive veterinary medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Pedro Jimenez-BluhmDepartment of Preventive Animal Medicine, Faculty of Veterinary Sciences, University of Chile, Santiago, Chile.
Alejandra SepulvedaDepartment of Preventive Animal Medicine, Faculty of Veterinary Sciences, University of Chile, Santiago, Chile.
Cecilia BaumbergerDepartment of Preventive Animal Medicine, Faculty of Veterinary Sciences, University of Chile, Santiago, Chile.
Francisca Di PilloNúcleo de Investigaciones Aplicadas en Ciencias Veterinarias y Agronómicas, Facultad de Medicina Veterinaria y Agronomía, Universidad de Las Américas, Santiago, Chile.
Soledad RuizNúcleo de Investigaciones Aplicadas en Ciencias Veterinarias y Agronómicas, Facultad de Medicina Veterinaria y Agronomía, Universidad de Las Américas, Santiago, Chile.
Carla SalazarDepartment of Preventive Animal Medicine, Faculty of Veterinary Sciences, University of Chile, Santiago, Chile.
Victor MarambioDepartment of Preventive Animal Medicine, Faculty of Veterinary Sciences, University of Chile, Santiago, Chile.
Fernanda BerriosDepartment of Preventive Animal Medicine, Faculty of Veterinary Sciences, University of Chile, Santiago, Chile.
Pablo GaldamesDepartment of Preventive Animal Medicine, Faculty of Veterinary Sciences, University of Chile, Santiago, Chile.
Alicia AmaroDepartment of Preventive Animal Medicine, Faculty of Veterinary Sciences, University of Chile, Santiago, Chile.
David TapiaDepartment of Preventive Animal Medicine, Faculty of Veterinary Sciences, University of Chile, Santiago, Chile.
Bridgett SharpDepartment of Infectious Diseases, St. Jude Children's Hospital, Memphis, TN, USA.
Pamela FreidenDepartment of Infectious Diseases, St. Jude Children's Hospital, Memphis, TN, USA.
Victoria MeliopoulosDepartment of Infectious Diseases, St. Jude Children's Hospital, Memphis, TN, USA.
Stacey Schultz-CherryDepartment of Infectious Diseases, St. Jude Children's Hospital, Memphis, TN, USA.
Christopher Hamilton-WestDepartment of Preventive Animal Medicine, Faculty of Veterinary Sciences, University of Chile, Santiago, Chile. Electronic address: christopher.hamilton@veterinaria.uchile.cl.
University of Chile · CLSt. Jude Children's Research Hospital · USUniversity of the Americas · CL

Funding

NIAID NIH HHS HHSN272201400006C
6 · The paper itself

Abstract

As companion animals, dogs and cats live in close contact with humans, generating the possibility of interspecies pathogen transmission events. Equine origin H3N8 and avian origin H5N1 influenza virus have been reported in dogs and cats respectively since 2004 with outbreaks associated with different strains recorded for both species in Asia and North America. To date, there have been no reports of influenza viruses from companion animals in South America. To fill this gap in knowledge, we performed active epidemiological surveillance in shelters that received abandoned animals, backyard production systems and veterinary clinics between May 2017 and January 2019 to estimate the burden of influenza infection in cats and dogs in the central region of Chile. Blood samples, oropharyngeal swabs or both were collected for influenza A virus detection by RT-qPCR, NP-ELISA, and hemagglutination inhibition assay. Logistic regression models were performed to assess the association between NP-ELISA-positivity and variables including sex and animal origin. The percentage of ELISA-positive samples was 43.5 % (95 % CI: 37.0-50.1) and 23.3 % (95 % CI: 10.6-42.7) for dogs and cats, respectively. No association was found between NP-ELISA results and sex or animal origin for either dogs or cats. Two ELISA positive samples showed hemagglutination inhibition titers against pandemic H1N1 influenza. One dog sample tested positive by RT-qPCR, indicating an overall RT-qPCR positivity in dogs of 1.1 % (95 % CI: 0.05-6.7). None of the tested cat samples were positive by this assay.

Indexed as

CatsChileDogsELISAInfluenza ART-qPCRSerology

Identifiers

PMID33892254
PMCPMC8521552
OpenAlexW3155549684

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.