Evidence map›Paper›PMID 33892190›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2021

Dramatic rise in seroprevalence rates of SARS-CoV-2 antibodies among healthy blood donors: The evolution of a pandemic.

Maher A Sughayer, Asem Mansour, Abeer Al Nuirat, Lina Souan, Mohammad Ghanem, Mahmoud Siag

Open access · goldAbstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. High seroprevalence for SARS-CoV-2 infection in South America, but still not enough for herd immunity!International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Pooled it
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  10. Confirmed circulation of SARS-CoV-2 in Irish blood donors prior to first national notification of infection.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2022
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  14. Sero-prevalence of SARS-CoV-2 antibodies in blood donors during the third wave of infection in Norway, winter/spring 2021.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maher A SughayerDepartment of Pathology and Laboratory Medicine, King Hussein Cancer Center, Amman, Jordan. Electronic address: Msughayer@KHCC.jo.
Asem MansourDepartment of Radiology, and CEO, King Hussein Cancer Center, Jordan.
Abeer Al NuiratDepartment of Pathology and Laboratory Medicine, King Hussein Cancer Center, Amman, Jordan.
Lina SouanDepartment of Pathology and Laboratory Medicine, King Hussein Cancer Center, Amman, Jordan.
Mohammad GhanemDepartment of Pathology and Laboratory Medicine, King Hussein Cancer Center, Amman, Jordan.
Mahmoud SiagDepartment of Pathology and Laboratory Medicine, King Hussein Cancer Center, Amman, Jordan.
King Hussein Cancer Center · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeroprevalence studies of SARS-CoV-2 antibodies are useful in assessing the epidemiological status in the community, and the degree of spread.

objectiveTo study the seroprevalence rates of SARS-CoV-2 antibodies among healthy blood donors in Jordan, at various points of time and as the pandemic evolves in the community.

methodsIn total, 1374 blood donor samples, from three groups, were tested for SARS-CoV-2 total immunoglobulin antibodies. In the first group, samples from 734 individuals (from donations made between January and June 2020) were tested in June. In the second group, 348 individuals were tested in September 2020. The third group of 292 individuals was tested in February 2021. A qualitative assay was used for testing (specificity 99.8%, sensitivity 100%).

resultsThe first two groups, from January-June and September 2020, when confirmed Covid-19 cases numbered between several hundred and 3000, showed a seroprevalence rate of 0% (95% CI 0.00-0.51%). The third group (early February 2021), when the number of confirmed cases had reached 100 times that of September 2020, revealed a seroprevalence of 27.4% (95% CI 22.5-32.9%).

conclusionsA dramatic rise in seroprevalence of SARS-CoV-2 antibodies was seen among healthy blood donors in Jordan, in parallel with widespread intracommunity transmission of the disease. This information is useful for assessing the degree of herd immunity, and provides for better understanding of the pandemic.

Indexed as

Blood DonorsAdolescentAdultAntibodies, ViralCOVID-19FemaleHumansJordanMaleMiddle AgedSARS-CoV-2Seroepidemiologic StudiesYoung AdultAntibodies, ViralBlood donorsCovid-19SARS-CoV-2 antibodiesSeroprevalence

Identifiers

PMID33892190
PMCPMC8057684
OpenAlexW3133861041

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.