ArticleAmerican journal of respiratory cell and molecular biology2021
Leptin Induces Epigenetic Regulation of Transient Receptor Potential Melastatin 7 in Rat Adrenal Pheochromocytoma Cells.
Article in American journal of respiratory cell and molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Epigenetic Silencing of Carotid Body TRPM7 Attenuates Hypertension in Obese Mice.bioRxiv : the preprint server for biology · 2026Article
- Diet-induced obesity in mice increases carotid body chemosensitivity via the leptin-TRPM7 pathway.The Journal of physiology · 2025Article
- Adipose Tissue-Derived Adipokines in Vascular Physiology and Pathophysiology: Insights and Implications.Comprehensive Physiology · 2025Review
- Epigenetic Reprogramming Drives Epithelial Disruption in Chronic Obstructive Pulmonary Disease.American journal of respiratory cell and molecular biology · 2024Article
- Epigenetic modifications in obesity-associated diseases.MedComm · 2024Review
- Carotid body denervation improves hyperglycemia in obese mice.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- TRPM7 channels regulate breathing during sleep in obesity by acting peripherally in the carotid bodies.The Journal of physiology · 2022Article
- PLAGL1 Gene Demethylation Induced by Epigallocatechin Gallate Promotes Pheochromocytoma Cell Apoptosis Via Wnt/β-catenin Signaling Pathway.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- TRP Channels as Molecular Targets to Relieve Endocrine-Related Diseases.Frontiers in molecular biosciences · 2022Review
- Maternal obesity and ovarian failure: is leptin the culprit?Animal reproduction · 2022Article
- Does the Epigenome Hold Clues to Leptin-associated Hypertension in Obesity?American journal of respiratory cell and molecular biology · 2021Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Obesity elevates the plasma level of leptin, which has been associated with hypertension. Our recent studies in mice demonstrated that leptin increases blood pressure by activating the carotid sinus nerve, which transmits the chemosensory input from carotid bodies (CBs) to the medullary centers, and that the effect of leptin is mediated via
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.