Evidence map›Paper›PMID 33891819›Full record

ArticleJournal of the American Chemical Society2021

Reducing Challenges in Organic Synthesis with Stereoselective Hydrogenation and Tandem Catalysis.

Patrick D Parker, Xintong Hou, Vy M Dong

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. StereoPHIP: Stereoselective Parahydrogen-Induced Polarization.Angewandte Chemie (International ed. in English) · 2023
    Article
  8. Journal of the American Chemical Society · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patrick D ParkerDepartment of Chemistry, University of California, Irvine, California 92697, United States.
Xintong HouDepartment of Chemistry, University of California, Irvine, California 92697, United States.
Vy M DongDepartment of Chemistry, University of California, Irvine, California 92697, United States.ORCID 0000-0002-8099-1048

Funding

Innovative Tools for Chemical Synthesis: Metal-Hydride Catalysis, Medicinal Motifs, and Molecular ProbesR35GM127071 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Vy M Dong · 2018 to 2026
$4.9M
NIGMS NIH HHS R35 GM127071
6 · The paper itself

Abstract

Tandem catalysis enables the rapid construction of complex architectures from simple building blocks. This Perspective shares our interest in combining stereoselective hydrogenation with transformations such as isomerization, oxidation, and epimerization to solve diverse challenges. We highlight the use of tandem hydrogenation for preparing complex natural products from simple prochiral building blocks and present tandem catalysis involving transfer hydrogenation and dynamic kinetic resolution. Finally, we underline recent breakthroughs and opportunities for asymmetric hydrogenation.

Indexed as

CatalysisHydrogenationMolecular StructureOrganic ChemicalsOxidation-ReductionStereoisomerismOrganic Chemicals

Identifiers

PMID33891819
PMCPMC9141585

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.