Evidence map›Paper›PMID 33891656›Full record

ArticlePloS one2021

A novel approach to dry weight adjustments for dialysis patients using machine learning.

Hae Ri Kim, Hong Jin Bae, Jae Wan Jeon, Young Rok Ham, Ki Ryang Na, Kang Wook Lee, Yun Kyong Hyon, Dae Eun Choi

Registry-linked trialAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06279156 (Optimal Frequency of Total Body Water Measurements by Bioelectrical Impedance Analysis to Prevent Intradialytic Hypotension), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06279156 nacompletednot on this mapstarted 2022, after this paper: background citation

Optimal Frequency of Total Body Water Measurements by Bioelectrical Impedance Analysis to Prevent Intradialytic Hypotension

TypeinterventionalSponsorThammasat University HospitalRan2022 to 2023Enrolled94ConditionsIntradialytic Hypotension, End Stage Renal Disease on DialysisArmsBioelectrical Impedance Analysis (BIA)
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Artificial intelligence and digital health for volume maintenance in hemodialysis patients.Hemodialysis international. International Symposium on Home Hemodialysis · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hae Ri KimDivision of Nephrology, Department of Internal Medicine, Chungnam National University Sejong Hospital, Sejong, South Korea.ORCID 0000-0001-8766-6064
Hong Jin BaeDivision of Nephrology, Department of Internal Medicine, Cheongju St. Mary's Hospital, Cheongju, South Korea.
Jae Wan JeonDivision of Nephrology, Department of Internal Medicine, Chungnam National University Sejong Hospital, Sejong, South Korea.
Young Rok HamDepartment of Nephrology, Medical School, Chungnam National University, Daejeon, South Korea.
Ki Ryang NaDepartment of Nephrology, Medical School, Chungnam National University, Daejeon, South Korea.
Kang Wook LeeDepartment of Nephrology, Medical School, Chungnam National University, Daejeon, South Korea.
Yun Kyong HyonMedical Mathematics Division, National Institute for Mathematical Sciences, Daejeon, South Korea.
Dae Eun ChoiDepartment of Nephrology, Medical School, Chungnam National University, Daejeon, South Korea.ORCID 0000-0003-2870-3958

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsKnowledge of the proper dry weight plays a critical role in the efficiency of dialysis and the survival of hemodialysis patients. Recently, bioimpedance spectroscopy(BIS) has been widely used for set dry weight in hemodialysis patients. However, BIS is often misrepresented in clinical healthy weight. In this study, we tried to predict the clinically proper dry weight (DWCP) using machine learning for patient's clinical information including BIS. We then analyze the factors that influence the prediction of the clinical dry weight.

methodsAs a retrospective, single center study, data of 1672 hemodialysis patients were reviewed. DWCP data were collected when the dry weight was measured using the BIS (DWBIS). The gap between the two (GapDW) was calculated and then grouped and analyzed based on gaps of 1 kg and 2 kg.

resultsBased on the gap between DWBIS and DWCP, 972, 303, and 384 patients were placed in groups with gaps of <1 kg, ≧1kg and <2 kg, and ≧2 kg, respectively. For less than 1 kg and 2 kg of GapDW, It can be seen that the average accuracies for the two groups are 83% and 72%, respectively, in usign XGBoost machine learning. As GapDW increases, it is more difficult to predict the target property. As GapDW increase, the mean values of hemoglobin, total protein, serum albumin, creatinine, phosphorus, potassium, and the fat tissue index tended to decrease. However, the height, total body water, extracellular water (ECW), and ECW to intracellular water ratio tended to increase.

conclusionsMachine learning made it slightly easier to predict DWCP based on DWBIS under limited conditions and gave better insights into predicting DWCP. Malnutrition-related factors and ECW were important in reflecting the differences between DWBIS and DWCP.

Indexed as

Machine LearningRenal DialysisAdipose TissueAgedBody WaterBody WeightCreatinineElectric ImpedanceExtracellular SpaceFemaleHemoglobinsHumansKidney Failure, ChronicMaleMiddle AgedSerum AlbuminCreatinineHemoglobinsSerum Albumin

Identifiers

PMID33891656
PMCPMC8064601

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.