Evidence map›Paper›PMID 33891534›Full record

ArticleThe Journal of general virology2021

Investigative study into whether an insect repellent has virucidal activity against SARS-CoV-2.

Sophie J Smither, Lin S Eastaugh, James S Findlay, Thomas R Laws, Stephen N Marriott, Stuart Notman, Lyn M O'Brien, Amanda L Phelps, Mark Richards, David Ulaeto and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of general virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Prospects of Coffee Leaf against SARS-CoV-2 Infection.International journal of biological sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Sophie J SmitherChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, SP4 0JQ, UK.
Lin S EastaughChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, SP4 0JQ, UK.
James S FindlayChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, SP4 0JQ, UK.
Thomas R LawsChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, SP4 0JQ, UK.
Stephen N MarriottChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, SP4 0JQ, UK.
Stuart NotmanChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, SP4 0JQ, UK.
Lyn M O'BrienChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, SP4 0JQ, UK.
Amanda L PhelpsChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, SP4 0JQ, UK.
Mark RichardsChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, SP4 0JQ, UK.
David UlaetoChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, SP4 0JQ, UK.
Pat WattsChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, SP4 0JQ, UK.
Mark S LeverChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, SP4 0JQ, UK.
Norman GovanChemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Wiltshire, SP4 0JQ, UK.
Defence Science and Technology Laboratory · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A small-scale study with Mosi-guard Natural spray, an insect repellent containing Citriodiol, was performed to determine if it has virucidal activity against SARS-CoV-2. A liquid test examined the activity of the insect repellent and the individual components for virucidal activity. A surface contact test looked at the activity of the insect repellent when impregnated on a latex surface as a synthetic skin for potential topical prophylactic application. Both Mosi-guard Natural spray and Citriodiol, as well as other components of the repellent, had virucidal activity in the liquid contact test. On a latex surface used to simulate treated skin, the titre of SARS-CoV-2 was less over time on the Mosi-guard Natural-treated surface but virus was still recovered.

Indexed as

COVID-19 Drug TreatmentAntiviral AgentsHumansInsect RepellentsPlant ExtractsSARS-CoV-2Antiviral AgentscitriodiolInsect RepellentsPlant Extractsanti-viral activityCitriodiolinsect repellentSARS-CoV-2skin

Identifiers

PMID33891534
PMCPMC8290268
OpenAlexW3155665056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.