Evidence map›Paper›PMID 33891193›Full record

ArticleJournal of materials science. Materials in medicine2021

Cytocompatibility of Ti-xZr alloys as dental implant materials.

Pinghua Ou, Cong Hao, Jue Liu, Rengui He, Baoqi Wang, Jianming Ruan

Open access · goldAbstract read
In one paragraph

Article in Journal of materials science. Materials in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Shaping the Structure and Properties of TiOMaterials (Basel, Switzerland) · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Bone response in vivo of Ti-45Zr alloy as dental implant material.Journal of materials science. Materials in medicine · 2022
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Pinghua OuState Key Laboratory of Powder Metallurgy, Central South University, Changsha, 410083, PR China.
Cong HaoDepartment of Orthopedics, Xiangya Hospital Central South University, Changsha, 410008, Hunan, PR China.
Jue LiuHunan Province Key Laboratory of Engineering Rheology, Central South University of Forestry and Technology, Changsha, 410004, PR China.
Rengui HeState Key Laboratory of Powder Metallurgy, Central South University, Changsha, 410083, PR China.
Baoqi WangState Key Laboratory of Powder Metallurgy, Central South University, Changsha, 410083, PR China.
Jianming RuanState Key Laboratory of Powder Metallurgy, Central South University, Changsha, 410083, PR China. jianming@csu.edu.cn.ORCID http://orcid.org/0000-0002-0472-7982
Central South University · CNCentral South University of Forestry and Technology · CN

Funding

Natural Science Foundation of Hunan Province 2020JJ5985Young Scientists Fund 51904357
6 · The paper itself

Abstract

Ti-xZr (x = 5, 15, 25, 35, 45% wt%) alloys with low elastic modulus and high mechanical strength were fabricated as a novel implant material. The biocompatibility of the Ti-xZr alloys was evaluated by osteoblast-like cell line (MG63) in terms of cytotoxicity, proliferation, adhesion, and osteogenic induction using CCK-8 and live/dead cell assays, electron microscopy, and real-time PCR. The Ti-xZr alloys were non-toxic and showed superior biomechanics compared to commercially pure titanium (cpTi). Ti-45Zr had the optimum strength/elastic modulus ratio and osteogenic activity, thus is a promising to used as dental implants.

Indexed as

Biocompatible MaterialsDental ImplantsMaterials TestingAlloysCell LineCell ProliferationCell SurvivalHumansOsteoblastsOsteogenesisTitaniumZirconiumAlloysBiocompatible MaterialsDental ImplantsTitaniumZirconium

Identifiers

PMID33891193
PMCPMC8064977
OpenAlexW3153775611

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.