Evidence map›Paper›PMID 33890854›Full record

ArticleeLife2021

Tyramine induces dynamic RNP granule remodeling and translation activation in the Drosophila brain.

Nadia Formicola, Marjorie Heim, Jérémy Dufourt, Anne-Sophie Lancelot, Akira Nakamura, Mounia Lagha, Florence Besse

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  7. Review
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  10. Review
  11. The lncRNAGenes & development · 2024
    Article
  12. Review
  13. Emerging Roles of RNA-Binding Proteins in Neurodevelopment.Journal of developmental biology · 2022
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Nadia FormicolaUniversité Côte d'Azur, CNRS, Inserm, Institut de Biologie Valrose, Nice, France.ORCID https://orcid.org/0000-0002-2039-1323
Marjorie HeimUniversité Côte d'Azur, CNRS, Inserm, Institut de Biologie Valrose, Nice, France.ORCID https://orcid.org/0000-0002-7858-4822
Jérémy DufourtInstitut de Génétique Moléculaire de Montpellier, University of Montpellier, Montpellier, France.ORCID https://orcid.org/0000-0003-4043-7250
Anne-Sophie LancelotUniversité Côte d'Azur, CNRS, Inserm, Institut de Biologie Valrose, Nice, France.
Akira NakamuraDepartment of Germline Development, Institute of Molecular Embryology and Genetics, and Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.ORCID http://orcid.org/0000-0001-6506-9146
Mounia LaghaInstitut de Génétique Moléculaire de Montpellier, University of Montpellier, Montpellier, France.ORCID https://orcid.org/0000-0002-7082-1950
Florence BesseUniversité Côte d'Azur, CNRS, Inserm, Institut de Biologie Valrose, Nice, France.ORCID https://orcid.org/0000-0003-4672-1068
Centre National de la Recherche Scientifique · FRUniversité de Montpellier · FRKumamoto University · JP

Funding

Agence Nationale de la Recherche ANR-11-LABX-0028-01Agence Nationale de la Recherche ANR-15-CE12-0016Agence Nationale de la Recherche ANR-20-CE16-0010-01Fondation pour la Recherche Médicale DEQ20180339161H2020 European Research Council SyncDevHuman Frontier Science Program CDAJapan Society for the Promotion of Science KAKENHI-17H03686
6 · The paper itself

Abstract

Ribonucleoprotein (RNP) granules are dynamic condensates enriched in regulatory RNA binding proteins (RBPs) and RNAs under tight spatiotemporal control. Extensive recent work has investigated the molecular principles underlying RNP granule assembly, unraveling that they form through the self-association of RNP components into dynamic networks of interactions. How endogenous RNP granules respond to external stimuli to regulate RNA fate is still largely unknown. Here, we demonstrate through high-resolution imaging of intact

Indexed as

Protein Processing, Post-TranslationalAnimalsBrainCytoplasmic GranulesDrosophila melanogasterDrosophila ProteinsFemaleMaleNeurotransmitter AgentsRibonucleoproteinsRNA-Binding ProteinsTyramineDrosophila ProteinsNeurotransmitter AgentsRibonucleoproteinsRNA-Binding ProteinsTyraminecell biologyD. melanogasterDrosophilalive-imagingneuronRNA binding proteinsRNP condensatestranslation

Identifiers

PMID33890854
PMCPMC8064753
OpenAlexW3156839822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.