Evidence map›Paper›PMID 33890480›Full record

ArticleJournal of the American Heart Association2021

Geographic Variation in Trends and Disparities in Heart Failure Mortality in the United States, 1999 to 2017.

Peter A Glynn, Rebecca Molsberry, Katharine Harrington, Nilay S Shah, Lucia C Petito, Clyde W Yancy, Mercedes R Carnethon, Donald M Lloyd-Jones, Sadiya S Khan

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 78 citations in OpenAlex.

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  9. Inpatient mortality following hip fracture in the United States: an updated analysis of over one million cases.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026
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  11. Regional disparities in the care and outcomes of atrial fibrillation patients in a universal health care system: a population-based cohort study.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Peter A GlynnDepartment of Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Rebecca MolsberryDepartment of Epidemiology, Human Genetics, and Environmental Sciences School of Public Health University of Texas Health Science Center Dallas TX.
Katharine HarringtonDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Nilay S ShahDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Lucia C PetitoDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Clyde W YancyDivision of Cardiology Department of Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Mercedes R CarnethonDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Donald M Lloyd-JonesDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Sadiya S KhanDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Northwestern University · USUniversity of Texas Health Science Center at Dallas · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI ELBERT S. HUANG · 2011 to 2026
$10.0M
Northwestern University Clinical and Translational Science Institute (NUCATS)KL2TR001424 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SHARMA, LEENA · 2015 to 2023
$8.1M
The Claude D. Pepper Older Americans Independence Center (OAIC) at Northwestern UniversityP30AG059988 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BRADLEY, SARA · 2020 to 2024
$7.1M
A self-regulation approach to diabetes adherence into emerging adulthoodR01DK092939 · NIDDK · UNIVERSITY OF UTAH · PI BERG, CYNTHIA A, WIEBE, DEBORAH J · 2011 to 2015
$2.7M
NCATS NIH HHS KL2 TR001424NCATS NIH HHS UL1 TR001422NIA NIH HHS P30 AG059988NIDDK NIH HHS P30 DK092949NIDDK NIH HHS R01 DK092939
6 · The paper itself

Abstract

Background Cardiovascular disease mortality related to heart failure (HF) is rising in the United States. It is unknown whether trends in HF mortality are consistent across geographic areas and are associated with state-level variation in cardiovascular health (CVH). The goal of the present study was to assess regional and state-level trends in cardiovascular disease mortality related to HF and their association with variation in state-level CVH. Methods and Results Age-adjusted mortality rates (AAMR) per 100 000 attributable to HF were ascertained using the Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research from 1999 to 2017. CVH at the state-level was quantified using the Behavioral Risk Factor Surveillance System. Linear regression was used to assess temporal trends in HF AAMR were examined by census region and state and to examine the association between state-level CVH and HF AAMR. AAMR attributable to HF declined from 1999 to 2011 and increased between 2011 and 2017 across all census regions. Annual increases after 2011 were greatest in the Midwest (β=1.14 [95% CI, 0.75, 1.53]) and South (β=0.96 [0.66, 1.26]). States in the South and Midwest consistently had the highest HF AAMR in all time periods, with Mississippi having the highest AAMR (109.6 [104.5, 114.6] in 2017). Within race‒sex groups, consistent geographic patterns were observed. The variability in HF AAMR was associated with state-level CVH (

Indexed as

ForecastingHealth StatusAdultAgedAged, 80 and overCross-Sectional StudiesFemaleFollow-Up StudiesHealthcare DisparitiesHeart FailureHumansMaleMiddle AgedRetrospective StudiesSurvival RateUnited Statesgeographic variationhealth disparitiesheart failureprevention

Identifiers

PMID33890480
PMCPMC8200738
OpenAlexW3152915923

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.