ArticleInternational journal of legal medicine2021
Scopolamine fatal outcome in an inmate after buscopan® smoking.
Article in International journal of legal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 14 citations in OpenAlex.
- The Current Status of Virtual Autopsy Using Combined Imaging Modalities: A Scoping Review.Journal of clinical medicine · 2025Review
- Perioperative considerations for patients exposed to hallucinogens.Regional anesthesia and pain medicine · 2024Review
- "Eco-friendly HPLC method for analysis of dipyrone and hyoscine in different matrices with biomonitoring".Scientific reports · 2024Article
- Hyoscine N-butylbromide inhalation: they know, how about you?World journal of emergency medicine · 2023Article
- Misuse of Anticholinergic Medications: A Systematic Review.Biomedicines · 2022Review
- Scopolamine fatal outcome in an inmate after buscopan® smoking.International journal of legal medicine · 2021Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Scopolamine is an alkaloid which acts as competitive antagonists to acetylcholine at central and peripheral muscarinic receptors. We report the case of a 41-year-old male convict with a 27-year history of cannabis abuse who suddenly died in the bed of his cell after having smoked buscopan® tablets. Since both abuse of substances and recent physical assaults had been reported, we opted for a comprehensive approach (post-mortem computed tomography CT (PMCT), full forensic autopsy, and toxicology testing) to determine which was the cause of the death. Virtopsy found significant cerebral edema and lungs edema that were confirmed at the autopsy and at the histopathological examination. Scopolamine was detected in peripheral blood at the toxic concentration of 14 ng/mL in blood and at 263 ng/mL in urine, and scopolamine butyl bromide at 17 ng/mL in blood and 90 ng/mL in urine. Quetiapine, mirtazapine, lorazepam, diazepam, and metabolites and valproate were also detected (at therapeutic concentrations). Inmates, especially when they have a history of drug abuse, are at risk to use any substance they can find for recreational purposes. In prisons, active surveillance on the management and assumption of prescribed drugs could avoid fatal acute intoxication.
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Registered trials
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