ArticlePediatric cardiology2021
Causes of Death in Infants and Children with Congenital Heart Disease.
Article in Pediatric cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 18 citations in OpenAlex.
- Characteristics of children with congenital heart defects and their caregivers in three U.S. sites: the Congenital Heart Survey To Recognize Outcomes Needs and well-beinG of KIDS (CHSTRONG KIDS).Progress in pediatric cardiology · 2026Article
- Synthetic embryos: current progress, application and challenges.Reproductive biology and endocrinology : RB&E · 2026Review
- Risk factors for early secondary infections after cardiopulmonary bypass in children with congenital heart disease: a single-center analysis of 265 cases.Translational pediatrics · 2025Article
- Electrocardiographic markers of hypertrophy in children: revisiting R/S overlap and the Katz-Wachtel phenomenon.Frontiers in pediatrics · 2025Article
- Classification of Fetal Congenital Heart Disease by Prenatal Ultrasound and Its Diagnostic Value.International journal of general medicine · 2025Article
- Cor Triatriatum: an uncommon congenital anomaly - the experience of a tertiary care center in a developing country.Frontiers in cardiovascular medicine · 2025Article
- Outcomes after cancer diagnosis in children and adult patients with congenital heart disease in Sweden: a registry-based cohort study.BMJ open · 2024Article
- Pediatric Cardiac Surgery Complications and the Risk Factors: A Single-Center Study.The journal of Tehran Heart Center · 2024Article
- SomaticExperimental and therapeutic medicine · 2024Article
- Discovery ofAmerican journal of translational research · 2024Article
- Article
- A new era of stem cell and developmental biology: from blastoids to synthetic embryos and beyond.Experimental & molecular medicine · 2023Review
- Causes of death in children with congenital anomalies up to age 10 in eight European countries.BMJ paediatrics open · 2023Article
- Habilitation of Executive Functions in Pediatric Congenital Heart Disease Patients through LEGOHealthcare (Basel, Switzerland) · 2022Article
- Identification ofDiagnostics (Basel, Switzerland) · 2022Article
- A novelExperimental and therapeutic medicine · 2022Article
Corrections and comments
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Authors and funding
12 authors at 9 institutions in 1 country.
Funding
Abstract
With improved surgical outcomes, infants and children with congenital heart disease (CHD) may die from other causes of death (COD) other than CHD. We sought to describe the COD in youth with CHD in North Carolina (NC). Patients from birth to 20 years of age with a healthcare encounter between 2008 and 2013 in NC were identified by ICD-9 code. Patients who could be linked to a NC death certificate between 2008 and 2016 were included. Patients were divided by CHD subtypes (severe, shunt, valve, other). COD was compared between groups. Records of 35,542 patients < 20 years old were evaluated. There were 15,277 infants with an annual mortality rate of 3.5 deaths per 100 live births. The most frequent COD in infants (age < 1 year) were CHD (31.7%), lung disease (16.1%), and infection (11.4%). In 20,265 children (age 1 to < 20 years), there was annual mortality rate of 9.7 deaths per 1000 at risk. The most frequent COD in children were CHD (34.2%), neurologic disease (10.2%), and infection (9.5%). In the severe subtype, CHD was the most common COD. In infants with shunt-type CHD disease, lung disease (19.5%) was the most common COD. The mortality rate in infants was three times higher when compared to children. CHD is the most common underlying COD, but in those with shunt-type lesions, extra-cardiac COD is more common. A multidisciplinary approach in CHD patients, where development of best practice models regarding comorbid conditions such as lung disease and neurologic disease could improve outcomes in this patient population.
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