Evidence map›Paper›PMID 33889838›Full record

ReviewMaterials today. Bio2021

Scaffold-based developmental tissue engineering strategies for ectodermal organ regeneration.

N Contessi Negrini, A Angelova Volponi, C A Higgins, P T Sharpe, A D Celiz

Open access · goldAbstract readReview
In one paragraph

Review in Materials today. Bio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Crosslinker-freeMaterials today. Bio · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Biomimetic Gland Models with Engineered Stratagems.Research (Washington, D.C.) · 2023
    Review
  9. Article
  10. Review
  11. Bioengineering in salivary gland regeneration.Journal of biomedical science · 2022
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

N Contessi NegriniDepartment of Bioengineering, Imperial College London, London, UK.
A Angelova VolponiCentre for Craniofacial and Regenerative Biology, King's College London, London, UK.
C A HigginsDepartment of Bioengineering, Imperial College London, London, UK.
P T SharpeCentre for Craniofacial and Regenerative Biology, King's College London, London, UK.
A D CelizDepartment of Bioengineering, Imperial College London, London, UK.
Imperial College London · GBKing's College London · GB

Funding

Medical Research Council MR/S034757/1
6 · The paper itself

Abstract

Tissue engineering (TE) is a multidisciplinary research field aiming at the regeneration, restoration, or replacement of damaged tissues and organs. Classical TE approaches combine scaffolds, cells and soluble factors to fabricate constructs mimicking the native tissue to be regenerated. However, to date, limited success in clinical translations has been achieved by classical TE approaches, because of the lack of satisfactory biomorphological and biofunctional features of the obtained constructs. Developmental TE has emerged as a novel TE paradigm to obtain tissues and organs with correct biomorphology and biofunctionality by mimicking the morphogenetic processes leading to the tissue/organ generation in the embryo. Ectodermal appendages, for instance, develop

Indexed as

Cell cocultureDevelopmentalEpithelial-mesenchymal interactionGland regenerationHair follicle regenerationtissue engineeringTooth regeneration

Identifiers

PMID33889838
PMCPMC8050778
OpenAlexW3135425539

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.