Evidence map›Paper›PMID 33889813›Full record

ArticleiScience2021

Fat-body brummer lipase determines survival and cardiac function during starvation in

Annelie Blumrich, Georg Vogler, Sandra Dresen, Soda Balla Diop, Carsten Jaeger, Sarah Leberer, Jana Grune, Eva K Wirth, Beata Hoeft, Kostja Renko and 5 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Annelie BlumrichCharité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research, CCR, Hessische Str. 3-4, 10115 Berlin, Germany.
Georg VoglerDevelopment, Aging and Regeneration Program, Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
Sandra DresenCharité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research, CCR, Hessische Str. 3-4, 10115 Berlin, Germany.
Soda Balla DiopDevelopment, Aging and Regeneration Program, Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
Carsten JaegerFederal Institute for Materials Research and Testing (BAM), Berlin, Germany.
Sarah LebererCharité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research, CCR, Hessische Str. 3-4, 10115 Berlin, Germany.
Jana GruneDZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany.
Eva K WirthDZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany.
Beata HoeftCharité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research, CCR, Hessische Str. 3-4, 10115 Berlin, Germany.
Kostja RenkoCharité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Experimental Endocrinology, Berlin, Germany.
Anna Foryst-LudwigCharité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research, CCR, Hessische Str. 3-4, 10115 Berlin, Germany.
Joachim SprangerDZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany.
Stephan SigristInstitute of Biology/Genetics, Freie Universität Berlin, Berlin, Germany.
Rolf BodmerDevelopment, Aging and Regeneration Program, Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
Ulrich KintscherCharité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research, CCR, Hessische Str. 3-4, 10115 Berlin, Germany.
Humboldt-Universität zu Berlin · DESanford Burnham Prebys Medical Discovery Institute · USFederal Institute For Materials Research and Testing · DEFreie Universität Berlin · DE

Funding

HEART DEVELOPMENT IN DROSOPHILAR01HL054732 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BODMER, ROLF · 1995 to 2024
$11.3M
Genetic Pathways in Ceramide-Associated Lipotoxic Cardiomyopathy and Heart FailureR01HL149992 · NHLBI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI BODMER, ROLF · 2020 to 2023
$1.9M
NHLBI NIH HHS R01 HL054732NHLBI NIH HHS R01 HL149992
6 · The paper itself

Abstract

The cross talk between adipose tissue and the heart has an increasing importance for cardiac function under physiological and pathological conditions. This study characterizes the role of fat body lipolysis for cardiac function in

Indexed as

LipidomicsMetabolomicsMolecular Physiology

Identifiers

PMID33889813
PMCPMC8050372
OpenAlexW3135460273

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.