Evidence map›Paper›PMID 33889794›Full record

ArticleCurrent developments in nutrition2021

A Prospective Analysis of Plasma Phospholipid Fatty Acids and Breast Cancer Risk in 2 Provinces in Canada.

Marnie Newell, Sunita Ghosh, Susan Goruk, Mohammedreza Pakseresht, Jennifer E Vena, Trevor J B Dummer, Catherine J Field

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current developments in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Marnie NewellDepartment of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, Canada.ORCID https://orcid.org/0000-0001-5668-7698
Sunita GhoshDepartment of Medical Oncology, University of Alberta, Edmonton, Canada.
Susan GorukDepartment of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, Canada.
Mohammedreza PaksereshtDepartment of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, Canada.
Jennifer E VenaDepartment of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, Canada.
Trevor J B DummerSchool of Population and Public Health, University of British Columbia, Vancouver, Canada.
Catherine J FieldDepartment of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, Canada.ORCID https://orcid.org/0000-0001-7285-4767
University of Alberta · CAAlberta Health Services · CAUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies suggest that fatty acid status influences breast cancer etiology, yet the roles of individual fatty acids in breast cancer risk are unclear, specifically when central adiposity and menopausal status are considered.

objectivesThis study examined the associations of fatty acid status with breast cancer risk including location, menopausal status, and waist-to-hip ratio as key variables.

methodsPrediagnostic plasma phospholipid fatty acids were measured in women with breast cancer (

resultsWomen from BCGP had a higher n-3 (ɷ-3) fatty acid status compared with the ATP (6.4% ± 0.08% vs. 5.3% ± 0.06%;

conclusionsOur findings suggest that regional variations in fatty acid status influence breast cancer risk, resulting in positive associations of total long-chain n-3 fatty acids in premenopausal ATP women and negative associations of these fatty acids in BCGP women with a waist-to-hip ratio below guidelines. This study highlights the complexity and difficulty in using fatty acid status to predict breast cancer risk in diverse populations without the consideration of other risk factors.

Indexed as

ATPBCGPbiomarkersbreast cancerfatty acidsrisk

Identifiers

PMID33889794
PMCPMC8049855
OpenAlexW3143370824

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.