Evidence map›Paper›PMID 33889707›Full record

ArticleOne health (Amsterdam, Netherlands)2021

An inactivated bacterium (paraprobiotic) expressing

Joseph F Urban, Martin K Nielsen, David Gazzola, Yue Xie, Ethiopia Beshah, Yan Hu, Hanchen Li, Florentina Rus, Kelly Flanagan, Austin Draper and 4 more

Open access · goldAbstract read
In one paragraph

Article in One health (Amsterdam, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Virulence · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Probiotics: an alternative anti-parasite therapy.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. The Effect of Supplementation withVeterinary sciences · 2022
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Joseph F UrbanU. S. Department of Agriculture, Agricultural Research Service, Beltsville Agricultural Research Center, Animal and Parasitic Diseases Laboratory, Beltsville, MD, United States of America.
Martin K NielsenM.H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY, United States of America.
David GazzolaProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, United States of America.
Yue XieU. S. Department of Agriculture, Agricultural Research Service, Beltsville Agricultural Research Center, Animal and Parasitic Diseases Laboratory, Beltsville, MD, United States of America.
Ethiopia BeshahU. S. Department of Agriculture, Agricultural Research Service, Beltsville Agricultural Research Center, Animal and Parasitic Diseases Laboratory, Beltsville, MD, United States of America.
Yan HuProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, United States of America.
Hanchen LiProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, United States of America.
Florentina RusProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, United States of America.
Kelly FlanaganProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, United States of America.
Austin DraperSynthetic Biomanufacturing Facility, Utah State University, Logan, UT, United States of America.
Sridhar VakalapudiSynthetic Biomanufacturing Facility, Utah State University, Logan, UT, United States of America.
Robert W LiU. S. Department of Agriculture, Agricultural Research Service, Beltsville Agricultural Research Center, Animal and Parasitic Diseases Laboratory, Beltsville, MD, United States of America.
Gary R OstroffProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, United States of America.
Raffi V AroianProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, United States of America.
University of Massachusetts Chan Medical School · USBeltsville Human Nutrition Research Center · USUtah State University · USAgricultural Research Service · USSichuan Agricultural University · CNUniversity of Kentucky · US

Funding

Function/optimization of a nematicidal Cry toxin arsenalR01AI056189 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI RAFFI V AROIAN · 2005 to 2026
$11.0M
Automated high throughput compound screening for broadly active anti-parasitic nematode drugsR01AI150866 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI AROIAN, RAFFI V · 2020 to 2024
$2.5M
NIAID NIH HHS R01 AI056189NIAID NIH HHS R01 AI150866
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnthelminticAscarisBacillus thuringiensisCry5B crystal proteinParaprobioticParascaris

Identifiers

PMID33889707
PMCPMC8048022
OpenAlexW3143717877

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.