Evidence map›Paper›PMID 33889669›Full record

ArticleBio-protocol2021

Analysis of TORC1-body Formation in Budding Yeast.

Ryan L Wallace, Eric Lu, Arron Sullivan, James E Hughes Hallett, Andrew P Capaldi

Open access · greenAbstract read
In one paragraph

Article in Bio-protocol, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ryan L WallaceDept of Molecular and Cellular Biology, University of Arizona, Tucson AZ, USA.
Eric LuDept of Molecular and Cellular Biology, University of Arizona, Tucson AZ, USA.
Arron SullivanDept of Molecular and Cellular Biology, University of Arizona, Tucson AZ, USA.
James E Hughes HallettDept of Molecular and Cellular Biology, University of Arizona, Tucson AZ, USA.
Andrew P CapaldiDept of Molecular and Cellular Biology, University of Arizona, Tucson AZ, USA.
University of Arizona · US

Funding

GRADUATE TRAINING IN BIOCHEMISTRY AND MOLECULAR BIOLOGYT32GM008659 · NIGMS · UNIVERSITY OF ARIZONA · PI CAPALDI, ANDREW PAUL, WEINERT, TED A. · 1997 to 2019
$5.3M
Dissection of the TORC1 Signaling Network in YeastR01GM097329 · NIGMS · UNIVERSITY OF ARIZONA · PI CAPALDI, ANDREW PAUL · 2011 to 2024
$4.7M
University of Arizona's Initiative for Maximizing Student Development (IMSD)T32GM139779 · NIGMS · UNIVERSITY OF ARIZONA · PI FRANS E TAX · 2022 to 2026
$2.9M
Graduate Training in Biochemistry and Molecular BiologyT32GM136536 · NIGMS · UNIVERSITY OF ARIZONA · PI Andrew Paul Capaldi, FRANS E TAX · 2020 to 2026
$2.4M
NIGMS NIH HHS R01 GM097329NIGMS NIH HHS T32 GM008659NIGMS NIH HHS T32 GM136536NIGMS NIH HHS T32 GM139779
6 · The paper itself

Abstract

The Target of Rapamycin kinase Complex I (TORC1) is the master regulator of cell growth and metabolism in eukaryotes. In the presence of pro-growth hormones and abundant nutrients, TORC1 is active and drives protein, lipid, and nucleotide synthesis by phosphorylating a wide range of proteins. In contrast, when nitrogen and/or glucose levels fall, TORC1 is inhibited, causing the cell to switch from anabolic to catabolic metabolism, and eventually enter a quiescent state. In the budding yeast

Indexed as

Kog1Kog1-bodyTor1TORC1TORC1-body

Identifiers

PMID33889669
PMCPMC8054205
OpenAlexW3144056990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.