Evidence map›Paper›PMID 33889388›Full record

ArticleJournal of nutritional science2021

Comparison of edible brown algae extracts for the inhibition of intestinal carbohydrate digestive enzymes involved in glucose release from the diet.

Maha Attjioui, Sinead Ryan, Aleksandra Konic Ristic, Thomas Higgins, Oscar Goñi, Eileen R Gibney, Joanna Tierney, Shane O'Connell

Open access · goldAbstract read
In one paragraph

Article in Journal of nutritional science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Evaluating the Potential ofPharmaceuticals (Basel, Switzerland) · 2023
    Review
  9. Cochayuyo (Foods (Basel, Switzerland) · 2023
    Article
  10. Review
  11. Anti-Steatotic Effects ofNutrients · 2023
    Article
  12. Characterization ofMarine drugs · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Maha AttjiouiShannon Applied Biotechnology Centre, Institute of Technology Tralee, Tralee, Ireland.
Sinead RyanMarigot Ltd., Carrigaline, Ireland.
Aleksandra Konic RisticUCD Institute of Food and Health, University College Dublin, Dublin, Ireland.
Thomas HigginsShannon Applied Biotechnology Centre, Institute of Technology Tralee, Tralee, Ireland.
Oscar GoñiMarigot Ltd., Carrigaline, Ireland.
Eileen R GibneyUCD Institute of Food and Health, University College Dublin, Dublin, Ireland.
Joanna TierneyShannon Applied Biotechnology Centre, Institute of Technology Tralee, Tralee, Ireland.
Shane O'ConnellShannon Applied Biotechnology Centre, Institute of Technology Tralee, Tralee, Ireland.
Munster Technological University · IEMarigot (Ireland) · IEUniversity College Dublin · IEShannon Applied Biotechnology Centre · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type II diabetes is considered the most common metabolic disorder in the developed world and currently affects about one in ten globally. A therapeutic target for the management of type II diabetes is the inhibition of α- glucosidase, an essential enzyme located at the brush border of the small intestinal epithelium. The inhibition of α-glucosidase results in reduced digestion of carbohydrates and a decrease in postprandial blood glucose. Although pharmaceutical synthetic inhibitors are available, these are usually associated with significant gastrointestinal side effects. In the present study, the impact of inhibitors derived from edible brown algae is being investigated and compared for their effect on glycaemic control. Carbohydrate- and polyphenolic-enriched extracts derived from

Indexed as

Blood GlucosePhaeophyceaePlant ExtractsSeaweedalpha-GlucosidasesCarbohydrate MetabolismDiabetes Mellitus, Type 2DietGlycoside Hydrolase InhibitorsHumansSucrasealpha-GlucosidasesBlood GlucoseGlycoside Hydrolase InhibitorsPlant ExtractsSucraseAFCE, combination of polyphenols from Aschophyllum nodosum and Fucus vesiculosus and chromiumAFE, polyphenol-rich extract from Aschophyllum nodosum and Fucus vesiculosusAscophyllum nodosumFucus vesiculosisHPAEC-PAD, high-performance anion exchange chromatography with pulsed amperometric detectionMANE, pure seaweed extract from Ascophyllum nodosumPCA, principal component analysispNPG, 4-nitrophenyl-β-d-glucopyranosideSeaweedType II diabetesUndaria pinnatifidaUPE, fucoidan-rich extract from Undaria pinnatifidaα-Glucosidase

Identifiers

PMID33889388
PMCPMC8057513
OpenAlexW3119744213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.