Evidence map›Paper›PMID 33889383›Full record

ArticleTherapeutic advances in psychopharmacology2021

Side-effect monitoring of continuing LAI antipsychotic medication in UK adult mental health services.

Carol Paton, Tom K J Craig, Brittany McConnell, Thomas R E Barnes

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in psychopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Carol PatonDivision of Psychiatry, Imperial College London, Du Cane Road, London, W12 ONN, UK.ORCID https://orcid.org/0000-0001-7756-1031
Tom K J CraigKing's College London Institute of Psychiatry, Psychology and Neuroscience, London, UK.
Brittany McConnellPrescribing Observatory for Mental Health, Centre for Quality Improvement, Royal College of Psychiatrists, London, UK.
Thomas R E BarnesDivision of Psychiatry, Imperial College London, London, UK.ORCID https://orcid.org/0000-0002-2324-656X
Imperial College London · GBKing's College London · GBRoyal College of Psychiatrists · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong-acting injectable (LAI) antipsychotic medications are used to optimise treatment outcomes in schizophrenia. Guaranteed medication delivery increases the responsibility of prescribers to monitor and manage adverse effects.

methodsIn the context of a quality improvement programme conducted by the Prescribing Observatory for Mental Health, a clinical audit addressed documented side-effect monitoring in patients prescribed continuing LAI antipsychotic medication under the care of United Kingdom adult mental health services.

resultsA total of 62 mental health services submitted data on 5169 patients prescribed LAI antipsychotic medication for more than a year. An assessment of side effects had been documented in the past year in 2304 (45%) cases.

conclusionThe data suggest a relatively low frequency of side-effect assessments, largely untargeted. This is likely to result in many adverse effects going unrecognised and unmanaged, thus failing to tackle their potential to confound mental state assessment and adversely affect physical health and adherence. Patients receiving LAI antipsychotic medication have regular contact with a healthcare professional who administers the medication, which provides an opportunity to potentially remedy this situation.

Indexed as

long-acting injectable antipsychotic medicationquality improvementschizophreniaside-effect assessment

Identifiers

PMID33889383
PMCPMC8040551
OpenAlexW3152668580

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.