Evidence map›Paper›PMID 33889318›Full record

ReviewJournal of community hospital internal medicine perspectives2021

Experimental therapies under investigation for COVID-19.

Reshma Golamari, Neeru Kapoor, Tanuja Devaraj, Nitasa Sahu, Courtney Kramer, Rohit Jain

Open access · goldAbstract readReview
In one paragraph

Review in Journal of community hospital internal medicine perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Reshma GolamariAssistant Professor of Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, USA.ORCID https://orcid.org/0000-0002-8842-9762
Neeru KapoorMicrobiologist, Maulana Azad Medical College, New Delhi, India.
Tanuja DevarajAssistant Professor of Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, USA.
Nitasa SahuAssistant Professor of Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, USA.ORCID https://orcid.org/0000-0002-4767-9095
Courtney KramerPenn State College of Medicine, Hershey, PA, USA.
Rohit JainAssistant Professor of Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, USA.
Penn State Milton S. Hershey Medical Center · USMaulana Azad Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus Disease 2019, caused by the virus, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), is a pandemic first discovered in Wuhan, China which has claimed over 1.7 million lives to date across the globe as of 24 December 2020. As the virus spreads across the world affecting millions of patients, there has been a massive movement to discover readily available and effective treatment options including vaccines. One of the limiting factors in treating the disease is its varied presentation and effect in patients, ranging from asymptomatic patients to those left in intensive care units, intubated and fighting for their lives. There are numerous clinical trials and small-scale studies underway to investigate potential treatment options. However, very few studies and drugs demonstrated efficacy while many more are under investigation, leaving care teams dependent on supportive care coupled with experimental treatment options. In this review, we summarize the various treatment options explored to treat COVID-19, discussing possible the mechanisms of fighting the virus.

Indexed as

COVID-19 treatmenthydroxychloroquinepandemic drugsremdesivirtherapies for COVID-19

Identifiers

PMID33889318
PMCPMC8043541
OpenAlexW3136898754

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.