Evidence map›Paper›PMID 33889285›Full record

ReviewWorld journal of diabetes2021

Maternal obesity as a risk factor for developing diabetes in offspring: An epigenetic point of view.

Simon Lecoutre, Salwan Maqdasy, Christophe Breton

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of diabetes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  16. Parental obesity-induced changes in developmental programming.Frontiers in cell and developmental biology · 2022
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Simon LecoutreDepartment of Medicine (H7), Karolinska Institutet, Stockholm 141-86, Sweden.
Salwan MaqdasyDepartment of Medicine (H7), Karolinska Institutet, Stockholm 141-86, Sweden.
Christophe BretonUniversity of Lille, EA4489, Maternal Malnutrition and Programming of Metabolic Diseases, Lille 59000, France.
Karolinska Institutet · SEUniversité Catholique de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the developmental origin of health and disease concept, the risk of many age-related diseases is not only determined by genetic and adult lifestyle factors but also by factors acting during early development. In particular, maternal obesity and neonatal accelerated growth predispose offspring to overweight and type 2 diabetes (T2D) in adulthood. This concept mainly relies on the developmental plasticity of adipose tissue and pancreatic β-cell programming in response to suboptimal

Indexed as

Adipose tissueBeta cellsDevelopmentEpigenomeObesityType 2 diabetes

Identifiers

PMID33889285
PMCPMC8040079
OpenAlexW3156790741

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.