Evidence map›Paper›PMID 33889268›Full record

ArticleThe Pan African medical journal2021

Hypercholesterolemia and related risk factors in a cohort of patients with diabetes and hypertension in Maputo, Mozambique.

Fausto Ciccacci, Noorjehan Majid, Sandro Petrolati, Mustafa Agy, Cacilda Massango, Stefano Orlando, Giovanni Guidotti, Paola Scarcella, Maria Cristina Marazzi

Open access · goldAbstract read
In one paragraph

Article in The Pan African medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Fausto CiccacciUniCamillus, Saint Camillus International University of Health Sciences, Rome, Italy.
Noorjehan MajidDisease Relief through Excellence and Advanced Means (DREAM) Program, Community of Sant'Egidio, Maputo, Mozambique.
Sandro PetrolatiDepartment of Cardioscience, San Camillo Hospital, Rome, Italy.
Mustafa AgyDisease Relief through Excellence and Advanced Means (DREAM) Program, Community of Sant'Egidio, Maputo, Mozambique.
Cacilda MassangoDisease Relief through Excellence and Advanced Means (DREAM) Program, Community of Sant'Egidio, Maputo, Mozambique.
Stefano OrlandoDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
Giovanni GuidottiAzienda Sanitaria Locale (ASL) Roma 1, Rome, Italy.
Paola ScarcellaDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
Maria Cristina MarazziLibera Università Maria Santissima Assunta (LUMSA), Rome, Italy.
University of Rome Tor Vergata · ITASL Roma · ITIRCCS San Camillo Hospital · ITLibera Università Maria SS. Assunta · ITSaint Camillus International University of Health and Medical Sciences · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionsome studies reported that 25.5% of African population presents hypercholesterolemia; however, epidemiology of hypercholesterolemia in Africa is poorly described. Mozambique is experiencing a constant growth of non-communicable diseases, but scarce data are available about hypercholesterolemia. Our study aims at describing the prevalence of hypercholesterolemia in patients with diabetes and hypertension in Mozambique and investigate possible risk factors.

methodswe conducted a cross-sectional study involving all the patients diagnosed with hypertension and/or diabetes from June 2018 to November 2020 in the Zimpeto DREAM Centre (Maputo, Mozambique). For each patient, anthropometric, clinical and laboratory data were collected. Hypercholesterolemia was defined as total blood cholesterol >200 mg/dL. Univariable and multivariable analysis were perfumed.

resultsa total of 885 patients were included, 76.2% (n=674) female. Hypertension alone was diagnosed in 670 (75.7%) patients, diabetes in 109 (12.3%) patients and 106 (11.9%) both diseases. Hypercholesterolemia was present in 410 (46.3%) patients and it was more prevalent in patients diagnosed with both diabetes and hypertension (52.8%), as compared to the patients diagnosed with hypertension (46.9%) or diabetes alone (36.7%). In the multivariable analysis, the only factors independently associated with hypercholesterolemia were female sex (aOR 1.77, 95% CI 1.26-2.48, p=0.001) and a body mass index >25kg/m

conclusionour results highlight the need for a specific focus on female and obese/overweight patients, especially if diagnosed with both hypertension and diabetes, to promptly detect metabolic disorders and establish temporary preventive measures for cardiovascular events.

Indexed as

AgedCohort StudiesCross-Sectional StudiesDiabetes MellitusFemaleHumansHypercholesterolemiaHypertensionMaleMiddle AgedMozambiqueObesityOverweightPrevalenceRisk FactorsSex Factorscardiovascular risk factorHypercholesterolemianon-communicable diseases

Identifiers

PMID33889268
PMCPMC8035689
OpenAlexW3128510547

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.