Evidence map›Paper›PMID 33889125›Full record

ReviewFrontiers in neurology2021

Current Trends, Controversies, and Future Directions in the Evaluation and Management of Superior Canal Dehiscence Syndrome.

Kristine Elisabeth Eberhard, Divya A Chari, Hideko Heidi Nakajima, Mads Klokker, Per Cayé-Thomasen, Daniel J Lee

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Round Window Reinforcement for Semicircular Canal Dehiscence Syndrome.The journal of international advanced otology · 2025
    Article
  7. Article
  8. Observational
  9. Arcuate eminence distance to temporal bone outer table in the middle fossa repair of superior canal dehiscence.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  10. [A case of adult temporal bone langerhans cell histiocytosis presenting as posterior canal dehiscence syndrome and literature review].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Review
  11. Review
  12. Review
  13. Article
  14. Superior semicircular canal dehiscence in relation with the superior petrosal sinus: our experience, surgical management and systematic review of literature.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Observational
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Kristine Elisabeth EberhardDepartment of Otolaryngology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United States.
Divya A ChariDepartment of Otolaryngology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United States.
Hideko Heidi NakajimaDepartment of Otolaryngology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United States.
Mads KlokkerCopenhagen Hearing and Balance Centre, Department of Otorhinolaryngology, Head and Neck Surgery & Audiology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Per Cayé-ThomasenCopenhagen Hearing and Balance Centre, Department of Otorhinolaryngology, Head and Neck Surgery & Audiology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Daniel J LeeDepartment of Otolaryngology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United States.
Harvard University · USCopenhagen University Hospital · DKMassachusetts Eye and Ear Infirmary · USRigshospitalet · DKUniversity of Copenhagen · DK

Funding

Middle-ear Mechanics in Normal and Pathological EarsR01DC004798 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI NAKAJIMA, HIDEKO HEIDI · 2001 to 2016
$4.9M
NIDCD NIH HHS R01 DC004798
6 · The paper itself

Abstract

Patients with superior canal dehiscence syndrome (SCDS) can present with a range of auditory and/or vestibular signs and symptoms that are associated with a bony defect of the superior semicircular canal (SSC). Over the past two decades, advances in diagnostic techniques have raised the awareness of SCDS and treatment approaches have been refined to improve patient outcomes. However, a number of challenges remain. First, there is currently no standardized clinical testing algorithm for quantifying the effects of superior canal dehiscence (SCD). SCDS mimics a number of common otologic disorders and established metrics such as supranormal bone conduction thresholds and vestibular evoked myogenic potential (VEMP) measurements; although useful in certain cases, have diagnostic limitations. Second, while high-resolution computed tomography (CT) is the gold standard for the detection of SCD, a bony defect does not always result in signs and symptoms. Third, even when SCD repair is indicated, there is a lack of consensus about nomenclature to describe the SCD, ideal surgical approach, specific repair techniques, and type of materials used. Finally, there is no established algorithm in evaluation of SCDS patients who fail primary repair and may be candidates for revision surgery. Herein, we will discuss both contemporary and emerging diagnostic approaches for patients with SCDS and highlight challenges and controversies in the management of this unique patient cohort.

Indexed as

craniotomydiagnosticSCDsemicircular canal dehiscenceSSCDsuperior canal dehiscencethird window syndrometransmastoid

Identifiers

PMID33889125
PMCPMC8055857
OpenAlexW3140059766

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.