Evidence map›Paper›PMID 33888821›Full record

ArticleScientific reports2021

En-face analysis of short posterior ciliary arteries crossing the sclera to choroid using wide-field swept-source optical coherence tomography.

R Lejoyeux, R Atia, K K Vupparaboina, M N Ibrahim, S Suthaharan, J A Sahel, K K Dansingani, J Chhablani

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Three-Dimensional Choroidal Contour Mapping in Healthy and Diseased Eyes.Translational vision science & technology · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Volumetric quantification of choroid and Haller's sublayer using OCT scans: An accurate and unified approach based on stratified smoothing.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2022
    Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

R LejoyeuxRothschild Foundation Hospital, 29 rue Manin, 75019, Paris, France.
R AtiaXV-XX Hospital, 28 rue de Charenton, 75012, Paris, France.
K K VupparaboinaDepartment of Ophthalmology, School of Medicine, University of Pittsburgh, 4200 Fifth Ave, Pittsburgh, PA, USA.
M N IbrahimDepartment of Electrical Engineering, Indian Institute of Technology Hyderabad, Telangana, 502285, India.
S SuthaharanDepartment of Computer Science, University of North Carolina ast Greensboro, Greensboro, NC, USA.
J A SahelUPMC Eye Center, University of Pittsburgh, 203 Lothrop Street, Pittsburgh, PA, 15213, USA.
K K DansinganiUPMC Eye Center, University of Pittsburgh, 203 Lothrop Street, Pittsburgh, PA, 15213, USA.
J ChhablaniUPMC Eye Center, University of Pittsburgh, 203 Lothrop Street, Pittsburgh, PA, 15213, USA. jay.chhablani@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To study the topographic distribution of the short posterior ciliary arteries (SPCA) entry sites into the choroid in normal eyes using structural en-face swept source optical coherence tomography (SS-OCT). Retrospective analysis of SS-OCT scans (wide-field structural SS-OCT 12 × 12 mm) of 13 healthy subjects was performed. Cross-sectional swept-source OCT scans derived from a volume scan were represented as en-face image display following the Choroid-Scleral Interface to obtain en-face OCT. SPCAs in their last scleral location before choroidal entrance were identified manually, counted and localized by two masked observers. Correlations between two masked observers were analyzed using inter- and intra-class correlation. Accuracy for the choroidal inner and outer border segmentation was 95-99%. Eighteen eyes from 13 normal subjects were included for SPCA analysis. The mean number of arteries was 13.8 ± 3.5 per eye. Thirty-six percent were in the center of the posterior pole image; however, 21% were in the temporal part of the posterior pole. Median accuracy of the detection is 0.94. The correlation between the two observers was fair (0.54). Our algorithm allows visualization of the SPCA at the posterior pole of the eye using wide-field en-face SS-OCT. It can also help the clinicians to study the SPCAs in numerous ocular diseases, particularly its relationship with focal choroidal diseases.

Indexed as

AlgorithmsChoroidCiliary ArteriesCross-Sectional StudiesFemaleHumansMaleRetrospective StudiesScleraTomography, Optical CoherenceVisual Acuity

Identifiers

PMID33888821
PMCPMC8062624

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.