ArticleScientific reports2021
Macro- and micro-structural cerebellar and cortical characteristics of cognitive empathy towards fictional characters in healthy individuals.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Female Cerebellum Seems Sociable; An iTBS Investigation.Cerebellum (London, England) · 2024Trial
- Psychological and neuro-morphological predictors of resilience in healthy adults: the whole is more than the sum of its parts.Frontiers in neuroscience · 2025Review
- The Cerebellum as an Embodying Machine.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024Review
- Grey-matter correlates of empathy in 4-Repeat Tauopathies.NPJ Parkinson's disease · 2023Article
- Cerebellar engagement in the attachment behavioral system.Scientific reports · 2022Article
- Involvement of the intrinsic functional network of the red nucleus in complex behavioral processing.Cerebral cortex communications · 2022Article
- New prospects on cerebellar reserve: Remarks on neuroprotective effects of experience in animals and humans.Frontiers in systems neuroscience · 2022Review
- Cerebellum, Embodied Emotions, and Psychological Traits.Advances in experimental medicine and biology · 2022Article
- Cerebellum and Emotion in Morality.Advances in experimental medicine and biology · 2022Article
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Few investigations have analyzed the neuroanatomical substrate of empathic capacities in healthy subjects, and most of them have neglected the potential involvement of cerebellar structures. The main aim of the present study was to investigate the associations between bilateral cerebellar macro- and micro-structural measures and levels of cognitive and affective trait empathy (measured by Interpersonal Reactivity Index, IRI) in a sample of 70 healthy subjects of both sexes. We also estimated morphometric variations of cerebral Gray Matter structures, to ascertain whether the potential empathy-related peculiarities in cerebellar areas were accompanied by structural differences in other cerebral regions. At macro-structural level, the volumetric differences were analyzed by Voxel-Based Morphometry (VBM)- and Region of Interest (ROI)-based approaches, and at a micro-structural level, we analyzed Diffusion Tensor Imaging (DTI) data, focusing in particular on Mean Diffusivity and Fractional Anisotropy. Fantasy IRI-subscale was found to be positively associated with volumes in right cerebellar Crus 2 and pars triangularis of inferior frontal gyrus. The here described morphological variations of cerebellar Crus 2 and pars triangularis allow to extend the traditional cortico-centric view of cognitive empathy to the cerebellar regions and indicate that in empathizing with fictional characters the cerebellar and frontal areas are co-recruited.
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