Evidence map›Paper›PMID 33888738›Full record

ArticleScientific reports2021

Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influenza viruses.

Sui-Yuan Chang, Kuo-Yen Huang, Tai-Ling Chao, Han-Chieh Kao, Yu-Hao Pang, Lin Lu, Chun-Lun Chiu, Hsin-Chang Huang, Ting-Jen Rachel Cheng, Jim-Min Fang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 42 citations in OpenAlex.

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  17. The healthier healthcare management models for COVID-19.Journal of infection and public health · 2021
    Review
  18. Nanotechnology-based therapeutic formulations in the battle against animal coronaviruses: an update.Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Sui-Yuan ChangDepartment of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, No. 1, Sec. 1, Ren-Ai Rd., Taipei, 10002, Taiwan.
Kuo-Yen HuangDepartment and Graduate Institute of Microbiology and Immunology, National Defense Medical Center, Taipei, 11490, Taiwan.
Tai-Ling ChaoDepartment of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, No. 1, Sec. 1, Ren-Ai Rd., Taipei, 10002, Taiwan.
Han-Chieh KaoDepartment of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, No. 1, Sec. 1, Ren-Ai Rd., Taipei, 10002, Taiwan.
Yu-Hao PangDepartment of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, No. 1, Sec. 1, Ren-Ai Rd., Taipei, 10002, Taiwan.
Lin LuTripod Nano Technology, No. 171, Sec. 1, Mei Shi Rd., Yang Mei District, Taoyuan, 32656, Taiwan.
Chun-Lun ChiuTripod Nano Technology, No. 171, Sec. 1, Mei Shi Rd., Yang Mei District, Taoyuan, 32656, Taiwan.
Hsin-Chang HuangTripod Nano Technology, No. 171, Sec. 1, Mei Shi Rd., Yang Mei District, Taoyuan, 32656, Taiwan.
Ting-Jen Rachel ChengThe Genomics Research Center, Academia Sinica, No. 128, Sec. 2, Academia Rd., Taipei, 11529, Taiwan.
Jim-Min FangThe Genomics Research Center, Academia Sinica, No. 128, Sec. 2, Academia Rd., Taipei, 11529, Taiwan. jmfang@ntu.edu.tw.
Pan-Chyr YangDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, No. 7, Chung-Shan South Rd., Taipei, 10002, Taiwan. pcyang@ntu.edu.tw.
National Taiwan University · TWGenomics Research Center, Academia Sinica · TWNational Taiwan University Hospital · TWNational Defense Medical Center · TW

Funding

Academia Sinica AS-SUMMIT-108Ministry of Science and Technolog MOST 107-0210-01-19-01Ministry of Science and Technology MOST107-2320-B-002-016-MY3Ministry of Science and Technology MOST 108-3114-Y-001-002
6 · The paper itself

Abstract

A metal nanoparticle composite, namely TPNT1, which contains Au-NP (1 ppm), Ag-NP (5 ppm), ZnO-NP (60 ppm) and ClO

Indexed as

Angiotensin-Converting Enzyme 2Antiviral AgentsDrug Resistance, ViralFood AdditivesGoldHEK293 CellsHumansInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H5N1 SubtypeMetal NanoparticlesNanocompositesOseltamivirParticle SizeProtein BindingSARS-CoV-2SilverACE2 protein, humanAngiotensin-Converting Enzyme 2Antiviral AgentsFood AdditivesGoldOseltamivirSilverSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2Zinc Oxide

Identifiers

PMID33888738
PMCPMC8062499
OpenAlexW3083547306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.